Anonsen C K, Lalakea M L, Hannley M
Department of Otolaryngology, Stanford University Medical Center, California.
Ann Otol Rhinol Laryngol. 1989 Sep;98(9):677-83. doi: 10.1177/000348948909800904.
Sensory stimuli to the larynx evoke a laryngeal adductor reflex mediated by the brain stem via superior and recurrent laryngeal nerves. Aberrant laryngeal reflexes have been proposed to explain a number of poorly understood disorders, including "reflex apnea," idiopathic laryngospasm, and sudden infant death syndrome. The purpose of the present study was to evaluate far field brain stem recordings following stimulation of the superior laryngeal nerve to determine whether laryngeal brain stem response is a valid measure of laryngeal activity at the brain stem level. The nerve was stimulated electrically in adult cats, and the resultant laryngeal adductor response as well as far field brain stem activity was recorded. For the latter, six reproducible positive and five reproducible negative waves were obtained via posterior pharyngeal (+) and posterior cervical (-) recording electrodes. Response threshold and latencies were measured and evaluated as a function of stimulus parameters. Wave latencies corresponded closely to those reported in prior near and far field evoked response recordings.
对喉部的感觉刺激会引发一种由脑干通过喉上神经和喉返神经介导的喉内收肌反射。异常的喉反射被认为可以解释一些难以理解的疾病,包括“反射性呼吸暂停”、特发性喉痉挛和婴儿猝死综合征。本研究的目的是评估刺激喉上神经后的远场脑干记录,以确定喉脑干反应是否是脑干水平喉活动的有效指标。在成年猫身上对该神经进行电刺激,并记录由此产生的喉内收肌反应以及远场脑干活动。对于后者,通过咽后(+)和颈后(-)记录电极获得了六个可重复的正波和五个可重复的负波。测量反应阈值和潜伏期,并根据刺激参数进行评估。波潜伏期与先前近场和远场诱发反应记录中报告的潜伏期密切对应。