Aiem A, Lagrange J L, Hery M
Ann Radiol (Paris). 1989;32(3):213-6.
The clinical and radiological responses after irradiation of brain metastases were compared in 50 patients. A complete response as evidenced by CT scan was achieved in 11 patients, whereas a clinical complete response was observed in 16 cases. There was only 35% agreement between the clinical and the radiological responses. In terms of patient survival, those in whom complete radiological response was obtained has a significantly longer survival time (p = 0.004). Therefore, in evaluating the treatment of brain metastases, it is preferable to determine both the clinical and the radiological responses. The latter seems to be more accurate and justifies the use of repeated CT scans in the follow-up of these patients.
对50例脑转移瘤患者放疗后的临床和影像学反应进行了比较。11例患者经CT扫描显示达到完全缓解，而16例观察到临床完全缓解。临床和影像学反应之间的一致性仅为35%。就患者生存而言，获得影像学完全缓解的患者生存时间显著更长（p = 0.004）。因此，在评估脑转移瘤的治疗时，最好同时确定临床和影像学反应。后者似乎更准确，这也证明了在这些患者的随访中重复进行CT扫描的合理性。
