Antony Suresh J, Cooper Leigh G
1205 N. Oregon, El Paso, Texas 79902, United States.
Department of Medicine, Section of Infectious Diseases, Texas Tech University Health Sciences Center, El Paso, Texas, United States.
Infect Disord Drug Targets. 2017;17(2):77-80. doi: 10.2174/1871526517666161108130148.
Prosthetic joint infections (PJI) result in significant morbidity, mortality and cost to patients and the health system. Traditional treatment involves a twostaged revision and occasionally a single staged revision along with intravenous antibiotics (IV) and or oral antibiotics for several weeks to months. The use of a single staged revision along with an antibiotic which has a prolonged half life and is bactericidal would be ideal. We present 2 patients who were treated successfully with a single stage revision/antibiotic spacer and a new novel long acting lipoglycopeptide called oritavancin.
人工关节感染（PJI）会给患者和医疗系统带来严重的发病率、死亡率和成本。传统治疗方法包括两阶段翻修，偶尔也会采用单阶段翻修，并联合静脉注射抗生素（IV）和/或口服抗生素持续数周或数月。采用单阶段翻修并使用半衰期长且具有杀菌作用的抗生素将是理想的治疗方案。我们介绍了2例通过单阶段翻修/抗生素间隔物以及一种名为奥利万星的新型长效脂糖肽成功治疗的患者。
