Branca D, Giron F, Conte L, Vincenti E, Scutari G
Department of Biological Chemistry, University of Padova, Italy.
Biochem Pharmacol. 1989 Sep 15;38(18):3045-8. doi: 10.1016/0006-2952(89)90013-0.
Rat livers have been perfused with a saline control medium or with a perfluorocarbon emulsion containing perfluorodecalin and N,N-perfluorodiethylcyclohexylamine, and the respiratory rates and transmembrane electrical potentials of mitochondria isolated following perfusion have been evaluated. The results indicate that the perfluorocarbon emulsion used, by providing a good oxygen supply to the perfused liver, allowed to preserve the efficiency of mitochondrial oxidative phosphorylation.
用生理盐水对照介质或含有全氟萘烷和N，N-全氟二乙基环己胺的全氟碳乳剂灌注大鼠肝脏，并评估灌注后分离的线粒体的呼吸速率和跨膜电位。结果表明，所使用的全氟碳乳剂通过为灌注肝脏提供良好的氧气供应，能够保持线粒体氧化磷酸化的效率。
