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向消除区域性麻疹迈进——全球,2000-2015 年。

Progress Toward Regional Measles Elimination - Worldwide, 2000-2015.

出版信息

MMWR Morb Mortal Wkly Rep. 2016 Nov 11;65(44):1228-1233. doi: 10.15585/mmwr.mm6544a6.

Abstract

Adopted in 2000, United Nations Millennium Development Goal 4 set a target to reduce child mortality by two thirds by 2015, with measles vaccination coverage as one of the progress indicators. In 2010, the World Health Assembly (WHA) set three milestones for measles control by 2015: 1) increase routine coverage with the first dose of measles-containing vaccine (MCV1) for children aged 1 year to ≥90% nationally and ≥80% in every district; 2) reduce global annual measles incidence to <5 cases per 1 million population; and 3) reduce global measles mortality by 95% from the 2000 estimate (1,2).* In 2012, WHA endorsed the Global Vaccine Action Plan with the objective to eliminate measles in four World Health Organization (WHO) regions by 2015. Countries in all six WHO regions have adopted measles elimination goals. Measles elimination is the absence of endemic measles transmission in a region or other defined geographical area for ≥12 months in the presence of a well performing surveillance system. This report updates a previous report (3) and describes progress toward global measles control milestones and regional measles elimination goals during 2000-2015. During this period, annual reported measles incidence decreased 75%, from 146 to 36 cases per 1 million persons, and annual estimated measles deaths decreased 79%, from 651,600 to 134,200. However, none of the 2015 milestones or elimination goals were met. Countries and their partners need to act urgently to secure political commitment, raise the visibility of measles, increase vaccination coverage, strengthen surveillance, and mitigate the threat of decreasing resources for immunization once polio eradication is achieved.

摘要

联合国千年发展目标 4 于 2000 年通过,目标是到 2015 年将儿童死亡率降低三分之二,麻疹疫苗接种覆盖率是进展指标之一。2010 年,世界卫生大会(WHA)为 2015 年的麻疹控制设定了三个里程碑:1)将儿童 1 岁时接种含麻疹成分疫苗(MCV1)的常规覆盖率提高到全国≥90%,每个地区≥80%;2)将全球年麻疹发病率降至每百万人<5 例;3)将全球麻疹死亡率从 2000 年的估计值降低 95%(1,2)。*2012 年,WHA 批准了《全球疫苗行动计划》,目标是到 2015 年在世界卫生组织(WHO)的四个区域消除麻疹。所有六个 WHO 区域的国家都通过了消除麻疹的目标。消除麻疹是指在存在运行良好的监测系统的情况下,一个区域或其他确定的地理区域中不存在地方性麻疹传播,且持续时间≥12 个月。本报告更新了之前的报告(3),并描述了 2000-2015 年期间全球麻疹控制里程碑和区域消除麻疹目标的进展情况。在此期间,年报告麻疹发病率下降了 75%,从每百万人 146 例降至 36 例,年估计麻疹死亡人数下降了 79%,从 651600 人降至 134200 人。然而,没有一个 2015 年的里程碑或消除目标得以实现。各国及其合作伙伴需要紧急采取行动,确保政治承诺,提高麻疹的可见度,提高疫苗接种覆盖率,加强监测,并减轻一旦消灭脊灰炎后免疫接种资源减少的威胁。

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