Dennis A, Hardy L
Clinical Associate Professor, Department of Obstetrics and Gynaecology and Department of Pharmacology, The University of Melbourne, Director of Anaesthesia Research and Staff Specialist Anaesthetist, Department of Anaesthesia, The Royal Women's Hospital, Melbourne, Victoria.
Hospital Medical Officer, The University of Melbourne and Department of Obstetrics and Gynaecology and Department of Anaesthesia, The Royal Women's Hospital, Melbourne, Victoria.
Anaesth Intensive Care. 2016 Nov;44(6):752-757. doi: 10.1177/0310057X1604400619.
Early warning systems (EWS), used to identify deteriorating hospitalised patients, are based on measurement of vital signs. When the patients are pregnant, most EWS still use non-pregnant reference ranges of vital signs to determine trigger thresholds. There are no published reference ranges for all vital signs in pregnancy. We aimed to define vital signs reference ranges for term pregnancy in the preoperative period, and to determine the appropriateness of EWS trigger criteria in pregnancy. We conducted a one-year retrospective study in a tertiary referral obstetric hospital. The study sample was healthy term women undergoing planned caesarean section (CS). Systolic blood pressure (SBP), diastolic blood pressure (DBP), heart rate (HR), oxygen saturation (SpO) and temperature were all measured automatically and data was extracted from the medical record. Two hundred and fifty-eight women met inclusion criteria. Results were (mean ± SD [standard deviation]) SBP 118 ± 11.2 mmHg, DBP 75 ± 10.3 mmHg, HR 84 ± 10.2 /minute, respiratory rate 18 ± 1.5 /minute, SpO 99% ± 1.0% and temperature 36.4°C ± 0.43°C. The reference ranges (mean ± 2SD) determined were SBP 96-140 mmHg, DBP 54-96 mmHg, HR 64-104/minute, RR 15-21 /minute, SpO 97%-100% and temperature 35.5°C-37.3°C. This study defined a reference range for vital signs in healthy term pregnant women undergoing CS. Study findings suggest that currently used criteria for EWS triggers, based on non-pregnant values, may be too extreme for timely detection of deteriorating pregnant patients. Further research examining the modified HR triggers of ≤50 and ≥110 /minute in pregnant women and their relationship to clinical outcomes is required.
用于识别住院病情恶化患者的早期预警系统(EWS)是基于生命体征的测量。当患者为孕妇时,大多数EWS仍使用非孕妇的生命体征参考范围来确定触发阈值。目前尚无关于孕期所有生命体征的已发表参考范围。我们旨在确定足月妊娠术前的生命体征参考范围,并确定EWS触发标准在孕期的适用性。我们在一家三级转诊产科医院进行了为期一年的回顾性研究。研究样本为计划行剖宫产术(CS)的健康足月孕妇。收缩压(SBP)、舒张压(DBP)、心率(HR)、血氧饱和度(SpO)和体温均自动测量,并从病历中提取数据。258名女性符合纳入标准。结果为(均值±标准差[SD]):SBP 118±11.2 mmHg,DBP 75±10.3 mmHg,HR 84±10.2次/分钟,呼吸频率18±1.5次/分钟,SpO 99%±1.0%,体温36.4°C±0.43°C。确定的参考范围(均值±2SD)为:SBP 96 - 140 mmHg,DBP 54 - 96 mmHg,HR 64 - 104次/分钟,RR 15 - 21次/分钟,SpO 97% - 100%,体温35.5°C - 37.3°C。本研究确定了计划行剖宫产术的健康足月孕妇生命体征的参考范围。研究结果表明,目前基于非孕妇值的EWS触发标准对于及时发现病情恶化的孕妇可能过于极端。需要进一步研究检查孕妇心率修改后的触发阈值≤50次/分钟和≥110次/分钟及其与临床结局的关系。