Ramírez Kennet, Zavala José, Morán David, Hernández Diana, Jiménez Alberto
Departments of Radiation Oncology, State Oncology Center, Avenida Lázaro Cárdenas número 208, esquina antiguo camino a Chiná, sector Las Flores. Código Postal, 24096, Campeche, México.
Departments of Pathology, State Oncology Center, Avenida Lázaro Cárdenas número 208, esquina antiguo camino a Chiná, sector Las Flores. Código Postal, 24096, Campeche, México.
J Med Case Rep. 2016 Nov 10;10(1):322. doi: 10.1186/s13256-016-1101-6.
Classic Kaposi's sarcoma is a lymphatic endothelial cell neoplasm usually present on the skin of the upper and lower extremities. Although it commonly affects human immunodeficiency virus positive patients, there have been some human immunodeficiency virus negative cases reported. We report an uncommon presentation of stage IV classic Kaposi's sarcoma in an human immunodeficiency virus negative patient in Latin America with complete clinical response using only radiation therapy treatment.
A 78-year-old Mexican man with no evidence of human immunodeficiency virus infection presented with a painful widespread dermatosis with maculopapular, nodular, violaceous lesions on his legs and ulcerated lesions on his feet. A biopsy confirmed the lesions as classic Kaposi's sarcoma. Radiotherapy treatment was delivered, prescribing a total dose of 30 Gy in 15 fractions with a complete clinical response within 15 months of follow-up.
This is an unusual case since it is uncommon to use radiation therapy as the single treatment in stage IV classic Kaposi's sarcoma; the efficacy of the treatment is shown in the impact in our patient's recurrence-free survival, local control, and palliation of our patient's symptoms.
经典型卡波西肉瘤是一种通常出现在上下肢皮肤的淋巴管内皮细胞瘤。虽然它常见于人类免疫缺陷病毒阳性患者，但也有一些人类免疫缺陷病毒阴性病例的报道。我们报告了拉丁美洲一名人类免疫缺陷病毒阴性患者出现的罕见的IV期经典型卡波西肉瘤，仅通过放射治疗就取得了完全的临床缓解。
一名78岁的墨西哥男性，无人类免疫缺陷病毒感染证据，出现了疼痛性广泛皮肤病，腿部有斑丘疹、结节、紫罗兰色病变，足部有溃疡病变。活检证实病变为经典型卡波西肉瘤。给予放射治疗，总剂量30 Gy，分15次给予，在随访的15个月内取得了完全的临床缓解。
这是一个不寻常的病例，因为在IV期经典型卡波西肉瘤中仅使用放射治疗作为单一治疗并不常见；治疗的有效性体现在对我们患者的无复发生存、局部控制以及症状缓解方面的影响。
