Faculty of Medicine, Department of Radiation Oncology, Karadeniz Technical University, Trabzon, Turkey.
Faculty of Medicine, Department of Dermatology, Ataturk University, Erzurum, Turkey.
Dermatol Ther. 2018 Jul;31(4):e12605. doi: 10.1111/dth.12605. Epub 2018 Apr 6.
Kaposi sarcoma is a rare adult neoplasm and there has been no certain consensus on standard treatment, either local or systemic. Radiotherapy is an effective, suitable treatment modality. Between 1996 and 2016, patients who were diagnosed with Kaposi sarcoma and referred to our clinic for radiotherapy were included in this retrospective study. Ninety-two patients were examined in total and it was diagnosed that all the patients had non-HIV associated Kaposi's sarcoma. There were 36 (39%) females and 56 (61%) males and female to male ratio was 2/3. Median age at presentation was 72 (30-93) years. Sixty-eight patients (77%) were treated with 8 Gy (1 fraction), 15 patients (16%) were treated with 20 Gy (2 Gy/fraction), four patients (4%) were treated 25 Gy (2.5 Gy/fraction), and five patients (6%) were treated 30 Gy (3 Gy/fraction). The median follow-up time was 72 (5-192) months. The complete response at 5 years was 91.6% with >20 Gy and 89.6% with 8 Gy. Radiotherapy is an effective, suitable treatment modality of Classic Kaposi sarcoma and usually, radiotherapy is well tolerated with minimal side effects.
卡波西肉瘤是一种罕见的成人肿瘤，局部或全身治疗均无明确的标准共识。放射治疗是一种有效的、合适的治疗方式。1996 年至 2016 年期间，在我院进行放射治疗的卡波西肉瘤患者被纳入本回顾性研究。共检查了 92 例患者，所有患者均被诊断为非 HIV 相关的卡波西肉瘤。其中女性 36 例（39%），男性 56 例（61%），女性与男性的比例为 2/3。发病时的中位年龄为 72 岁（30-93 岁）。68 例患者（77%）接受 8 Gy（1 个剂量）治疗，15 例患者（16%）接受 20 Gy（2 Gy/剂量）治疗，4 例患者（4%）接受 25 Gy（2.5 Gy/剂量）治疗，5 例患者（6%）接受 30 Gy（3 Gy/剂量）治疗。中位随访时间为 72 个月（5-192 个月）。接受>20 Gy 治疗的患者在 5 年内完全缓解率为 91.6%，接受 8 Gy 治疗的患者完全缓解率为 89.6%。放射治疗是经典卡波西肉瘤的有效且合适的治疗方式，通常放射治疗耐受性良好，副作用极小。
