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接受精神药物治疗女性的性功能障碍:一项基于医院的横断面研究。

Sexual Dysfunction among Females Receiving Psychotropic Medication: A Hospital-based Cross-sectional Study.

作者信息

Shetageri Veda N, Bhogale Govind S, Patil N M, Nayak R B, Chate S S

机构信息

Department of Psychiatry, MVJMC and RH, Bengaluru, Karnataka, India.

Department of Psychiatry, SNMC, Bagalkot, Karnataka, India.

出版信息

Indian J Psychol Med. 2016 Sep-Oct;38(5):447-454. doi: 10.4103/0253-7176.191379.

Abstract

BACKGROUND

Sexual dysfunction (SD) is a known adverse effect of psychotropic medications. Even though sexual difficulties are common among women; very few studies have been carried out in India.

OBJECTIVE

To study the prevalence and nature of SD among females receiving psychotropic medications and to compare the SD among female patients receiving antipsychotics and antidepressants.

MATERIALS AND METHODS

Female investigator conducted a hospital-based cross-sectional study on female patients visiting the psychiatry outpatient department. Patients meeting inclusion criteria were assessed for SD disorder as per Diagnostic and Statistical Manual of Mental Disorders 4 Edition Text Revision. SD severity was measured using Female Sexual Function Index (FSFI) scale.

RESULTS

The prevalence of SD in this study was 68.32%. There was more than one SD in 48 (47.52%). FSFI score was significantly low in patients with SD as compared to patients not having SD ( = 0.001). SD was more common in patients who were on combination of antidepressants and benzodiazepines than antidepressant alone or antipsychotic alone.

CONCLUSION

SD was prevalent in more than 50% of female patients on psychotropic drugs. Number of patients on individual psychotropic drugs was so small that a definite conclusion could not be drawn. Study emphasizes the need to carry out similar study on larger number of patients to get better insight into this problem.

摘要

背景

性功能障碍(SD)是精神药物已知的不良反应。尽管女性中性功能问题很常见,但在印度进行的相关研究却很少。

目的

研究接受精神药物治疗的女性中SD的患病率和性质,并比较接受抗精神病药物和抗抑郁药物治疗的女性患者中的SD情况。

材料与方法

女性研究者对到精神科门诊就诊的女性患者进行了一项基于医院的横断面研究。根据《精神疾病诊断与统计手册》第4版修订本,对符合纳入标准的患者进行SD障碍评估。使用女性性功能指数(FSFI)量表测量SD严重程度。

结果

本研究中SD的患病率为68.32%。48名(47.52%)患者存在不止一种SD。与无SD的患者相比,有SD的患者FSFI评分显著较低(P = 0.001)。与单独使用抗抑郁药或单独使用抗精神病药相比,同时使用抗抑郁药和苯二氮䓬类药物的患者中SD更常见。

结论

超过50%接受精神药物治疗的女性患者存在SD。使用单一精神药物的患者数量太少,无法得出明确结论。该研究强调需要对更多患者进行类似研究,以便更好地了解这一问题。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb72/5052959/e033559e934d/IJPsyM-38-447-g004.jpg

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