Damam Siva Prasad, Yeshala Veerabadram, Mukkara Ramasubba Reddy, Boorla Vivaswan, Kotha Rakesh
Department of Psychiatry, Osmania Medical College, Hyderabad, IND.
Department of Psychiatry, Government Medical College, Vikarabadh, Vikarabadh, IND.
Cureus. 2024 Aug 18;16(8):e67116. doi: 10.7759/cureus.67116. eCollection 2024 Aug.
Sexual dysfunction (SD) is a significant issue among psychiatric patients on psychotropic medications. This study aims to compare SD in patients using antipsychotics and antidepressants.
To evaluate the prevalence of SD and its effect on the quality of life among psychiatric patients on medications.
A cross-sectional study had been conducted with 150 participants (50 with schizophrenia, 50 with affective disorders, and 50 controls). SD was evaluated employing the Psychotropic-Related Sexual Dysfunction Questionnaire (PRSexDQ) and the Arizona Sexual Experience Scale (ASEX). The Quality of Life Enjoyment and Satisfaction Questionnaire-Short Form (Q-LES-Q-SF) was used to measure the quality of life. Data analysis techniques included Spearman's correlation test, one-way ANOVA, chi-square test, and descriptive statistics.
SD prevalence was 42% in affective disorders, 64% in schizophrenia, and 18% in controls. SD significantly correlated with a longer duration of psychotropic use and negatively impacted quality of life.
SD is prevalent among psychiatric patients on long-term medication, highlighting the need for strategies to manage these side effects.
性功能障碍（SD）是服用精神药物的精神病患者中的一个重要问题。本研究旨在比较使用抗精神病药物和抗抑郁药物的患者中的性功能障碍情况。
评估服用药物的精神病患者中性功能障碍的患病率及其对生活质量的影响。
对150名参与者（50名精神分裂症患者、50名情感障碍患者和50名对照者）进行了一项横断面研究。采用与精神药物相关的性功能障碍问卷（PRSexDQ）和亚利桑那性体验量表（ASEX）评估性功能障碍。使用生活享受与满意度问卷简表（Q-LES-Q-SF）来测量生活质量。数据分析技术包括Spearman相关性检验、单因素方差分析、卡方检验和描述性统计。
情感障碍患者中性功能障碍的患病率为42%，精神分裂症患者中为64%，对照者中为18%。性功能障碍与精神药物使用时间较长显著相关，并对生活质量产生负面影响。
性功能障碍在长期服药的精神病患者中很普遍，这凸显了应对这些副作用的策略的必要性。
