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首例由……引起的迟发性膝关节假体周围感染病例报告

First Case Report of a Late Onset Knee Periprosthetic Joint Infection Caused by .

作者信息

Neagoe V-I, Zytoun S, Neuhaus H-J

机构信息

Department of Orthopaedics and Traumatology, St. Vincenz-Hospital, 58706 Menden, Germany.

出版信息

Case Rep Orthop. 2016;2016:5053640. doi: 10.1155/2016/5053640. Epub 2016 Oct 19.

DOI:10.1155/2016/5053640
PMID:27833769
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5090070/
Abstract

is known as a Gram-positive, catalase-negative, and facultatively anaerobic fish pathogen. The association between spp. and human infectious diseases is described as being mainly associated with lumbar osteomyelitis, hepatic abscess, and infective endocarditis. In the literature of orthopedic post-prosthetic infections, was associated with a case of hip prosthetic infection in a fishmonger woman. We present the case of a 79-year-old male patient with multiple comorbidities, who is admitted to our center with a 5-day history of pain, swelling, and motility disorder of the right knee by the presence of a bicondylar knee replacement surgery, which was performed due to gonarthrosis 17 years ago. The radiographies of the right knee revealed no signs of displacement or loosening of the prothesis. After multiple radical debridements including VAC therapy and targeted antibiotic therapy we have managed to defeat the infection without exchange arthroplasty. Although we could not demonstrate the source of infection, we can only presume that in our case the source of infection was represented by the ingestion of possibly contaminated food. The patient had a habit of eating Nile perch fish () every 4 weeks. We illustrated once more the possibility of a late onset related orthopedic periprosthetic joint infection by multiple comorbidities.

摘要

被认为是一种革兰氏阳性、过氧化氢酶阴性、兼性厌氧的鱼类病原体。某菌属与人类传染病之间的关联主要被描述为与腰椎骨髓炎、肝脓肿和感染性心内膜炎有关。在骨科假体感染的文献中,某菌属与一名女鱼贩的髋关节假体感染病例有关。我们报告了一例79岁男性患者,该患者有多种合并症,因17年前因膝关节病行双髁膝关节置换手术,出现右膝疼痛、肿胀和活动障碍5天后来我院就诊。右膝X线片未显示假体移位或松动迹象。经过多次彻底清创,包括负压封闭引流治疗和针对性抗生素治疗,我们成功战胜了感染,无需进行关节置换术。虽然我们无法确定感染源,但我们只能推测在我们这个病例中,感染源可能是摄入了受污染的食物。该患者有每4周吃一次尼罗河鲈鱼的习惯。我们再次说明了多种合并症导致晚期某菌属相关骨科假体周围关节感染的可能性。

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本文引用的文献

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Lactococcus garvieae endocarditis in a patient with colonic diverticulosis: first case report in Italy and review of the literature.一名患有结肠憩室病患者的加氏乳球菌性心内膜炎:意大利首例病例报告及文献综述
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Primary infective spondylodiscitis caused by Lactococcus garvieae and a review of human L. garvieae infections.由乳球菌引起的原发性感染性脊椎骨髓炎,以及人类乳球菌感染的综述。
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First report of a hip prosthetic and joint infection caused by Lactococcus garvieae in a woman fishmonger.首例由格氏乳球菌引起的女性鱼贩人工髋关节假体及关节感染报告。
J Clin Microbiol. 2011 May;49(5):2074-6. doi: 10.1128/JCM.00065-11. Epub 2011 Mar 2.
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Phenotypic typing, technological properties and safety aspects of Lactococcus garvieae strains from dairy environments.来自乳制品环境的格氏乳球菌菌株的表型分型、技术特性及安全性方面
J Appl Microbiol. 2007 Aug;103(2):445-53. doi: 10.1111/j.1365-2672.2006.03265.x.
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Lactococcus garvieae infections in humans: possible association with aquaculture outbreaks.人感染格氏乳球菌:可能与水产养殖疫情有关。
Int J Clin Pract. 2007 Jan;61(1):68-73. doi: 10.1111/j.1742-1241.2006.00855.x. Epub 2006 May 16.
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A rare cause of infective endocarditis; Lactococcus garvieae.感染性心内膜炎的罕见病因;格氏乳球菌。
Int J Cardiol. 2007 Jan 8;114(2):286-7. doi: 10.1016/j.ijcard.2005.11.092. Epub 2006 Apr 17.
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Lactococcus garvieae septicemia with liver abscess in an immunosuppressed patient.一名免疫抑制患者发生加氏乳球菌败血症并伴有肝脓肿。
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