May Anthony C, Ehrlich Rachel L, Balashov Sergey, Ehrlich Garth D, Shanmugam Mayilvahanan, Fine Daniel H, Ramasubbu Narayanan, Mell Joshua Chang, Cugini Carla
Department of Oral Biology, Rutgers School of Dental Medicine, Newark, New Jersey, USA.
Department of Microbiology and Immunology, Center for Genomic Sciences (CGS), Institute for Molecular Medicine & Infectious Disease, Drexel University College of Medicine, Philadelphia, Pennsylvania, USA.
Genome Announc. 2016 Nov 10;4(6):e01285-16. doi: 10.1128/genomeA.01285-16.
We report here the complete genomic sequence and methylome of Aggregatibacter actinomycetemcomitans strain IDH781. This rough strain is used extensively as a model organism to characterize localized aggressive periodontitis pathogenesis, the basic biology and oral cavity colonization of A. actinomycetemcomitans, and its interactions with other members of the oral microbiome.
我们在此报告伴放线聚集杆菌IDH781菌株的完整基因组序列和甲基化组。这种粗糙型菌株被广泛用作模式生物,以表征局限性侵袭性牙周炎的发病机制、伴放线聚集杆菌的基础生物学特性和口腔定植情况,以及它与口腔微生物群其他成员的相互作用。