Witkowski Michal, Bissinger Andrzej, Grycewicz Tomasz, Lubinski Andrzej
Department of Invasive Cardiology and Arrhythmias, Medical University of Lodz, Lodz, Poland.
Department of Invasive Cardiology and Arrhythmias, Medical University of Lodz, Lodz, Poland.
Int J Cardiol. 2017 Jan 15;227:583-588. doi: 10.1016/j.ijcard.2016.10.097. Epub 2016 Nov 5.
Atrial fibrillation is the most common chronic arrhythmia. Due to diagnostic difficulties, the exact prevalence of silent atrial fibrillation is not precisely defined.
The main aim of the present study was to assess the prevalence of asymptomatic atrial fibrillation and the relation between clinical status and presence of symptoms of atrial fibrillation.
Fifty patients with implanted pacemaker with atrial fibrillation recording function and diagnosed paroxysmal atrial fibrillation were enrolled to the study in order to detect episodes of atrial fibrillation. Episodes lasting >1min were included into analysis. Patients were evaluated for presence of atrial fibrillation symptoms.
A total of 870 atrial fibrillation episodes were registered, the majority (93%) were asymptomatic. Episodes occurred more often during the day than during the night (p<0.001). Asymptomatic episodes occurred 13 times more frequently than symptomatic (p<0.001). Majority of episodes lasting up to 5min were asymptomatic, while episodes lasting over 24h were usually symptomatic (p<0.001). Furthermore, there were association between silent atrial fibrillation and lower HR (p=0.003), higher percentage of atrial (p=0.01) and ventricular pacing (p<0.001), male gender (p<0.001), presence of atrioventricular block (p<0.003), lower NYHA class (p<0.002), and calcium channel blockers (p=0.033) and diuretics intake (p<0.001).
In patients with bradycardia permanent pacemakers and paroxysmal atrial fibrillation, the proportion of asymptomatic episodes is very high. It was observed that shorter duration of the episodes, male gender, lower heart rate, presence of atrioventricular block, lower NYHA class, higher percentage of atrial and ventricular pacing, Ca blockers, and diuretics intake predisposed to silent atrial fibrillation.
心房颤动是最常见的慢性心律失常。由于诊断困难,无症状性心房颤动的确切患病率尚未明确界定。
本研究的主要目的是评估无症状性心房颤动的患病率以及临床状况与心房颤动症状之间的关系。
招募50例植入具有心房颤动记录功能起搏器且诊断为阵发性心房颤动的患者,以检测心房颤动发作情况。持续时间>1分钟的发作纳入分析。评估患者是否存在心房颤动症状。
共记录到870次心房颤动发作,大多数(93%)为无症状性发作。发作在白天比夜间更频繁(p<0.001)。无症状性发作比有症状性发作频繁13倍(p<0.001)。大多数持续时间达5分钟的发作是无症状性的,而持续超过24小时的发作通常是有症状的(p<0.001)。此外,无症状性心房颤动与较低的心率(p=0.003)、较高的心房起搏百分比(p=0.01)和心室起搏百分比(p<0.001)、男性性别(p<0.001)、存在房室传导阻滞(p<0.003)、较低的纽约心脏协会(NYHA)心功能分级(p<0.002)以及服用钙通道阻滞剂(p=0.033)和利尿剂(p<0.001)有关。
在患有缓慢性心律失常永久起搏器和阵发性心房颤动的患者中,无症状性发作的比例非常高。观察到发作持续时间较短、男性性别、心率较低、存在房室传导阻滞、NYHA心功能分级较低、较高的心房和心室起搏百分比、服用钙通道阻滞剂和利尿剂易发生无症状性心房颤动。