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脊髓损伤后止痛药滥用的风险:物质使用、人格和抑郁的作用。

Risk of Pain Medication Misuse After Spinal Cord Injury: The Role of Substance Use, Personality, and Depression.

作者信息

Clark Jillian M R, Cao Yue, Krause James S

机构信息

College of Health Professions, Medical University of South Carolina, Charleston, South Carolina; Department of Psychology, University of Missouri-Kansas City, Kansas City, Missouri.

College of Health Professions, Medical University of South Carolina, Charleston, South Carolina.

出版信息

J Pain. 2017 Feb;18(2):166-177. doi: 10.1016/j.jpain.2016.10.011. Epub 2016 Nov 9.

Abstract

UNLABELLED

Our purpose was to identify risk of pain medication misuse (PMM) among participants with spinal cord injury (SCI) by examining associations with multiple sets of risk factors including demographic and injury characteristics, pain experiences, frequency of pain medication use, substance use, personality, and depressive symptoms. Risk of PMM was defined by a cutoff score ≥30 measured using the Pain Medication Questionnaire (PMQ) and examined in 1,619 adults with traumatic SCI of at least 1 year duration who reported at least 1 painful condition and use of prescription pain medication using a cross-sectional design. Results indicated 17.6% of participants had scores of ≥30 on the PMQ. After controlling for demographic, injury, and pain characteristics, logistic regression analysis showed that being a current smoker, recently using cannabis (behavioral factors), and multiple psychological factors were associated with risk of PMM, as indicated by scores on the PMQ. These included elevated depressive symptomatology and exhibiting impulsive or anxious personality traits. Because risk of PMM is indicated in individuals with SCI, prescribers should assess and monitor multiple risk factors for PMM including substance use behaviors and psychological indicators.

PERSPECTIVE

This article identifies behavioral substance use and psychological factors associated with risk of PMM, measured using the PMQ, among those with SCI. Identification of these related variables will help health care professionals better prescribe and monitor pain medication use and/or misuse among individuals with SCI.

摘要

未标注

我们的目的是通过研究与多组风险因素的关联,来确定脊髓损伤(SCI)参与者中疼痛药物滥用(PMM)的风险,这些风险因素包括人口统计学和损伤特征、疼痛经历、疼痛药物使用频率、物质使用情况、个性和抑郁症状。PMM风险由使用疼痛药物问卷(PMQ)测量的截断分数≥30来定义,并在1619名创伤性SCI至少持续1年、报告至少1种疼痛状况且使用处方疼痛药物的成年人中采用横断面设计进行研究。结果表明,17.6%的参与者PMQ得分≥30。在控制了人口统计学、损伤和疼痛特征后,逻辑回归分析表明,当前吸烟、近期使用大麻(行为因素)以及多种心理因素与PMM风险相关,如PMQ得分所示。这些因素包括抑郁症状加重以及表现出冲动或焦虑的个性特征。由于SCI个体存在PMM风险,开处方者应评估和监测PMM的多种风险因素,包括物质使用行为和心理指标。

观点

本文确定了在SCI患者中,使用PMQ测量的与PMM风险相关的行为物质使用和心理因素。识别这些相关变量将有助于医疗保健专业人员更好地开处方和监测SCI个体的疼痛药物使用和/或滥用情况。

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