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超声引导下双侧肋间神经阻滞与传统患者自控静脉镇痛用于儿童Nuss手术后疼痛控制的比较:一项前瞻性随机研究

Comparison of Ultrasonography-guided Bilateral Intercostal Nerve Blocks and Conventional Patient-controlled Intravenous Analgesia for Pain Control After the Nuss Procedure in Children: A Prospective Randomized Study.

作者信息

Luo Mengqiang, Liu Xiaoming, Ning Li, Sun Yuan, Cai Ying, Shen Sai'e

机构信息

*Department of Anesthesiology ‡Pain Management Center, Xinhua Hospital, School of Medicine, Shanghai Jiaotong University †Department of Anesthesiology, Huashan Hospital, School of Medicine, Fudan University, Shanghai, China.

出版信息

Clin J Pain. 2017 Jul;33(7):604-610. doi: 10.1097/AJP.0000000000000449.

Abstract

OBJECTIVES

Patients experience severe pain after pectus excavatum (PE) surgery. The aim of this prospective, randomized study was to compare analgesic effects of ultrasonography-guided bilateral intercostal nerve blocks (UG-ICNBs) with those of conventional patient-controlled intravenous analgesia (PCIA) on acute pain after the Nuss procedure for PE repair in children.

METHODS

A prospective randomized study was performed in children with PE who were scheduled for the Nuss procedure. Participants were randomly assigned to receive either UG-ICNBs or PCIA for postoperative analgesia. Faces Pain Scale-Revised scores, opioid consumption, analgesia-associated side effects (respiratory depression, pruritus, nausea, vomiting) during the first 24 hours, and lengths of stay in the postanesthesia care unit (PACU) and hospital were recorded after the surgery.

RESULTS

Sixty-two children undergoing the Nuss procedure were enrolled in the trial. Faces Pain Scale-Revised scores were significantly decreased in the UG-ICNBs group compared with the PCIA group for up to 6 hours after surgery. The opioid doses required in the PACU and during the first 24 hours after surgery were significantly greater in the PCIA group compared with the UG-ICNBs group. Accordingly, patients in the UG-ICNBs group showed a lower incidence of analgesia-associated side effects and faster PACU discharge compared with the PCIA group.

CONCLUSIONS

Our study suggests that UG-ICNBs might be more effective than PCIA for postoperative analgesia in children who undergo the Nuss procedure for PE.

摘要

目的

漏斗胸(PE)手术后患者会经历严重疼痛。这项前瞻性随机研究的目的是比较超声引导下双侧肋间神经阻滞(UG - ICNBs)与传统患者自控静脉镇痛(PCIA)对儿童漏斗胸修复术(Nuss手术)后急性疼痛的镇痛效果。

方法

对计划接受Nuss手术的漏斗胸患儿进行前瞻性随机研究。参与者被随机分配接受UG - ICNBs或PCIA进行术后镇痛。记录术后24小时内的面部疼痛量表修订版评分、阿片类药物消耗量、镇痛相关副作用(呼吸抑制、瘙痒、恶心、呕吐)以及在麻醉后护理单元(PACU)和医院的住院时间。

结果

62例接受Nuss手术的儿童纳入试验。与PCIA组相比,UG - ICNBs组术后长达6小时的面部疼痛量表修订版评分显著降低。与UG - ICNBs组相比,PCIA组在PACU以及术后24小时内所需的阿片类药物剂量显著更高。因此,与PCIA组相比,UG - ICNBs组患者镇痛相关副作用的发生率更低,PACU出院更快。

结论

我们的研究表明,对于接受Nuss手术治疗漏斗胸的儿童,UG - ICNBs术后镇痛可能比PCIA更有效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a03/5462349/657539e83962/ajp-33-604-g001.jpg

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