Lukosiene Laura, Macas Andrius, Trepenaitis Darius, Kalibatiene Lina, Malcius Dalius, Barauskas Vidmantas
Lithuanian University of Health Sciences, Medical Academy, Lithuania.
J Pediatr Surg. 2014 Dec;49(12):1753-7. doi: 10.1016/j.jpedsurg.2014.09.014. Epub 2014 Oct 1.
The aim of this study was to investigate the efficacy of a single shot intercostal block for pain control in pediatric patients undergoing the Nuss procedure.
A double-blind, randomized, controlled study was performed. Thirty patients received a single shot bilateral intercostal block with levobupivacaine (L group) and 30 patients with 0.9 % saline (S group). Standardized baseline analgesia was applied for all patients. Morphine consumption, pain scores, respiratory depression, nausea and vomiting, and urinary retention were recorded every 3h for 48h after surgery.
The loading dose of morphine was lower (p<0.00001) in the L group. There were significantly lower morphine doses up to 6h after surgery and VAS scores up to 3h after surgery in the L group (p<0.001 and p=0.0003, respectively). The incidence of nausea and vomiting was lower in the L group (<0.00001). The incidence of urinary retention was lower in the L group (p=0.019).
A single shot IB is an effective additional treatment for pediatric patients undergoing the Nuss procedure and results in the reduced consumption of morphine, less postoperative pain, and fewer opioid-related adverse effects.
本研究旨在探讨单次肋间阻滞对接受努氏手术的儿科患者疼痛控制的疗效。
进行了一项双盲、随机、对照研究。30例患者接受了左旋布比卡因单次双侧肋间阻滞（L组），30例患者接受了0.9%生理盐水（S组）。所有患者均采用标准化的基线镇痛。术后48小时内每3小时记录一次吗啡用量、疼痛评分、呼吸抑制、恶心呕吐及尿潴留情况。
L组吗啡负荷剂量较低（p<0.0
