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瘢痕性睑外翻中的脂肪移植

Lipograft in cicatricial ectropion.

作者信息

Lupo Flavia, Ioppolo Leonardo, Pino Davide, Meduri Aessandro, d'Alcontres Francesco Stagno, R Colonna Michele, Delia Gabriele

出版信息

Ann Ital Chir. 2016;87:466-469.

PMID:27842016
Abstract

AIM

Cicatricial ectropion is secondary to an excessive scar contraction after trauma, burns, skin conditions, scarring skin tumours, medication, allergies, blepharoplasty complications 1,2. The estimates for ectropion incidence following removal of eyelid lesions have been reported as varying from 2.5% to 7% 3. A variety of surgical techniques can be applied to achieve the correct shape and position of lower lid 4-7. Fat grafts in association with other technique are commonly used in orbital reconstruction in a variety of procedures 8 including of the correction of cicatricial ectropion 9,10.

MATERIAL OF STUDY

The Authors propose the use of fat graft as only procedure for the correction of cicatricial lower eyelid ectropion. Two male patients with cicatricial ectropion were treated with this technique in two time and followed for 12 months.

RESULTS

Lipofilling for cicatricial eyelid ectropion give excellent outcomes, with release of the scar without recurrence, 11.

DISCUSSION

Autologous fat grafting has many clinical applications, and its use in Plastic Surgery is increasing: The key point is the presence into fat of Adipose stem cells (ASCs), that have been identified as an ideal source of cells for regenerative medicine, with potential and rapid improvement of healing process and complete recovery of tissue integrity after surgery to confirm the regenerative effect of fat graft.

CONCLUSION

Lipografting can be considered a safe and effective alternative procedure 12,13.

KEY WORDS

Defect of lower lid, Ectropion, Lipograft.

摘要

目的

瘢痕性睑外翻继发于创伤、烧伤、皮肤疾病、瘢痕性皮肤肿瘤、药物、过敏、眼睑成形术并发症等后的过度瘢痕收缩[1,2]。据报道,眼睑病变切除后睑外翻的发生率估计在2.5%至7%之间[3]。可应用多种手术技术来实现下睑的正确形状和位置[4-7]。脂肪移植与其他技术联合常用于各种眼眶重建手术[8],包括瘢痕性睑外翻的矫正[9,10]。

研究材料

作者提出将脂肪移植作为矫正瘢痕性下睑外翻的唯一手术方法。两名患有瘢痕性睑外翻的男性患者分两次接受了该技术治疗,并随访了12个月。

结果

脂肪填充治疗瘢痕性睑外翻效果极佳,瘢痕松解且无复发[11]。

讨论

自体脂肪移植有许多临床应用,其在整形手术中的应用正在增加:关键在于脂肪中存在脂肪干细胞(ASC),脂肪干细胞已被确定为再生医学的理想细胞来源,具有潜在且能快速改善愈合过程以及术后组织完整性完全恢复的能力,从而证实脂肪移植的再生效果。

结论

脂肪移植可被视为一种安全有效的替代手术方法[12,13]。

关键词

下睑缺损;睑外翻;脂肪移植

相似文献

1
Lipograft in cicatricial ectropion.瘢痕性睑外翻中的脂肪移植
Ann Ital Chir. 2016;87:466-469.
2
Efficacy of lateral eyelid-block excision with canthoplasty and full-thickness skin grafting in lower eyelid cicatricial ectropion.外侧睑板切除联合眦成形和全厚皮片移植治疗下眼睑瘢痕性外翻。
Acta Ophthalmol. 2019 Jun;97(4):e657-e661. doi: 10.1111/aos.13958. Epub 2018 Nov 2.
3
The hybrid approach for reconstruction of severely destructed lower eyelids: combination of skin grafting, temporary tarsorrhaphy, and autologous fat grafting for cicatricial ectropion after injection of commercial grade silicone.严重毁损下眼睑重建的混合方法:在注射商业级硅胶后用于瘢痕性睑外翻的皮肤移植、临时睑缘缝合术和自体脂肪移植联合应用
J Craniofac Surg. 2015 Jan;26(1):e8-10. doi: 10.1097/SCS.0000000000001218.
4
Viability of full-thickness skin grafts used for correction of cicatricial ectropion of lower eyelid in previously irradiated field in the periocular region.用于修复眼周区域曾放疗过的部位的下眼睑瘢痕性外翻的全厚皮片的成活率。
Head Neck. 2013 Jan;35(1):103-8. doi: 10.1002/hed.22934. Epub 2012 Jan 27.
5
Orbicularis Oculi Myocutaneous Flap for Upper Cicatricial Ectropion.眼轮匝肌肌皮瓣修复上睑瘢痕性睑外翻
J Craniofac Surg. 2016 Jan;27(1):70-3. doi: 10.1097/SCS.0000000000002262.
6
Autologous fat grafting for the correction of cicatricial ectropion.自体脂肪移植矫正瘢痕性睑外翻。
J Plast Reconstr Aesthet Surg. 2022 Dec;75(12):4496-4512. doi: 10.1016/j.bjps.2022.10.004. Epub 2022 Oct 13.
7
[Subperiosteal midface lift: an alternative to correct the cicatricial eyelid ectropion].[骨膜下中面部提升术:一种矫正瘢痕性睑外翻的替代方法]
Arq Bras Oftalmol. 2005 Jul-Aug;68(4):527-31. doi: 10.1590/s0004-27492005000400019. Epub 2005 Nov 22.
8
Aesthetic correction of severe cicatricial upper-eyelid ectropion with a retrograde postauricular island flap.采用逆行耳后岛状皮瓣矫正严重瘢痕性上睑外翻。
Aesthetic Plast Surg. 2013 Feb;37(1):95-101. doi: 10.1007/s00266-012-0009-9. Epub 2013 Jan 8.
9
Cicatricial ectropion surgery: a prospective study of long-term symptom control, patient satisfaction and anatomical success.瘢痕性眼睑外翻手术:长期症状控制、患者满意度和解剖成功的前瞻性研究。
Clin Exp Ophthalmol. 2018 Dec;46(9):1002-1007. doi: 10.1111/ceo.13338. Epub 2018 Jul 8.
10
Cicatricial ectropion correction in a patient with pyoderma gangrenosum: case report.坏疽性脓皮病患者瘢痕性睑外翻矫正:病例报告
Arq Bras Oftalmol. 2009 May-Jun;72(3):384-6. doi: 10.1590/s0004-27492009000300020.

引用本文的文献

1
Unlocking the versatile potential: Adipose-derived mesenchymal stem cells in ocular surface reconstruction and oculoplastics.释放多功能潜力:脂肪来源的间充质干细胞在眼表重建和眼部整形中的应用
World J Stem Cells. 2024 Feb 26;16(2):89-101. doi: 10.4252/wjsc.v16.i2.89.
2
The Use of Adipose-Derived Stem Cells (ADSCs) and Stromal Vascular Fraction (SVF) in Skin Scar Treatment-A Systematic Review of Clinical Studies.脂肪来源干细胞(ADSCs)和基质血管成分(SVF)在皮肤瘢痕治疗中的应用——临床研究的系统评价
J Clin Med. 2021 Aug 17;10(16):3637. doi: 10.3390/jcm10163637.
3
Correction of cicatricial ectropion using non-ablative fractional laser resurfacing.
使用非剥脱性分次激光表面重塑矫正瘢痕性睑外翻。
Lasers Med Sci. 2019 Feb;34(1):79-84. doi: 10.1007/s10103-018-2601-y. Epub 2018 Jul 28.