Isenalumhe Leidy L, Fridgen Olivia, Beaupin Lynda K, Quinn Gwendolyn P, Reed Damon R
Sarcoma Department, Moffitt Cancer Center, Tampa, FL, USA.
Cancer Control. 2016 Oct;23(4):424-433. doi: 10.1177/107327481602300414.
Cancer care for adolescents and young adults (AYAs) focuses on the care of patients aged 15 to 39 years. Historically, this group has favorable outcomes based on a preponderance of diagnoses such as thyroid cancers and Hodgkin lymphoma. Improvements in outcomes among the AYA population have lagged behind compared with younger and older populations.
We discuss and review recent progress in AYA patient care and highlight remaining disparities that exist, including financial disadvantages, need for fertility care, limited clinical trial availability, and other areas of evolving AYA-focused research.
Survival rates have not improved for this age group as they have for children and older adults. Disparities are present in the AYA population and have contributed to this lack of progress.
Recognizing disparities in the care of AYAs with cancer has led many medical specialty disciplines to improve the lives of these patients through advocacy, education, and resource development. Research addressing barriers to clinical trial enrollment in this population, quality-of-life issues, and the improvement of survivorship care is also under way.
青少年和青年成人(AYA)的癌症护理主要针对年龄在15至39岁的患者。从历史上看,基于甲状腺癌和霍奇金淋巴瘤等大量诊断,该群体的预后良好。与年轻和老年人群相比,AYA人群的预后改善较为滞后。
我们讨论并回顾了AYA患者护理的近期进展,并强调了仍然存在的差异,包括经济劣势、生育护理需求、临床试验可及性有限以及其他以AYA为重点的不断发展的研究领域。
该年龄组的生存率并未像儿童和老年人那样得到改善。AYA人群中存在差异,这导致了进展的缺乏。
认识到AYA癌症患者护理中的差异促使许多医学专业学科通过宣传、教育和资源开发来改善这些患者的生活。针对该人群临床试验入组障碍、生活质量问题以及生存护理改善的研究也正在进行。