伪装成葡萄膜炎-青光眼-前房积血综合征的虹膜前房非霍奇金淋巴瘤
Anterior Chamber Non-Hodgkin Lymphoma of the Iris Masquerading as Uveitis-Glaucoma-Hyphema Syndrome.
作者信息
Gauthier Angela C, Nguyen Alexander, Munday William R, Xu Mina L, Materin Miguel A
机构信息
Department of Ophthalmology and Visual Science, New Haven, Conn., USA.
Department of Pathology, Yale School of Medicine, New Haven, Conn., USA.
出版信息
Ocul Oncol Pathol. 2016 Oct;2(4):230-233. doi: 10.1159/000445119. Epub 2016 May 12.
PURPOSE
To report a case of iris non-Hodgkin lymphoma initially thought to be uveitis-glaucoma-hyphema (UGH) syndrome.
METHODS
We reviewed the clinical, radiographic, and histopathologic findings in a patient with recurrent hyphemas and increased ocular pressure who eventually was found to have a rapidly growing iris mass.
RESULTS
An 89-year-old man with a history of cataract extraction and mantle cell lymphoma developed recurrent hyphema, which was subsequently revealed to be due to an iris mass. A biopsy revealed non-Hodgkin lymphoma that could not be formally subclassified but was suspicious for mantle cell lymphoma. The tumor showed a partial response to ibrutinib.
CONCLUSION
Iris lymphoma can masquerade as a cause of recurrent hyphema after cataract extraction. Ophthalmologists should be aware of this presentation, especially in patients with a history of lymphoma.
目的
报告一例最初被认为是葡萄膜炎-青光眼-前房积血（UGH）综合征的虹膜非霍奇金淋巴瘤病例。
方法
我们回顾了一名反复前房积血且眼压升高患者的临床、影像学和组织病理学检查结果，该患者最终被发现有一个快速生长的虹膜肿物。
结果
一名有白内障摘除术和套细胞淋巴瘤病史的89岁男性出现反复前房积血，随后发现是由虹膜肿物所致。活检显示为非霍奇金淋巴瘤，无法正式分类，但怀疑为套细胞淋巴瘤。该肿瘤对伊布替尼有部分反应。
结论
虹膜淋巴瘤可伪装成白内障摘除术后反复前房积血的病因。眼科医生应了解这种表现，尤其是有淋巴瘤病史的患者。
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