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弥漫性大B细胞淋巴瘤虹膜转移误诊为原发性闭角型青光眼：一例报告并文献复习

Iris metastasis of diffuse large B-cell lymphoma misdiagnosed as primary angle-closure glaucoma: A case report and review of the literature.

作者信息

Li Zebing, Lin Zhongjing, Zhong Yisheng, Shen Xi

机构信息

Department of Ophthalmology, Ruijin Hospital, Affiliated Shanghai Jiaotong University School of Medicine, 197 Ruijin Er Road, 200025, Shanghai, China.

出版信息

Open Life Sci. 2021 Jan 20;16(1):61-68. doi: 10.1515/biol-2021-0008. eCollection 2021.

DOI:10.1515/biol-2021-0008
PMID:33817299
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7874580/
Abstract

BACKGROUND

Lymphoma with intraocular metastasis is an uncommon and serious disease. We describe a case of diffuse large B-cell lymphoma (DLBCL) with iris metastasis. Meanwhile, we refer to published case reports retrieved via a PubMed search to summarize this rare disease.

CASE PRESENTATION

Glaucoma and uveitis symptoms were found in the left eye of a 50-year-old woman upon admission to the hospital. After treatment and pathological examination, the iris of her left eye was diagnosed with DLBCL. Given the patient's unfavorable treatment options in the local hospital, primary enucleation was offered as a therapeutic option.

CONCLUSIONS

Iris metastasis of systemic lymphoma is an extremely rare ophthalmic disease with poor prognosis. Ophthalmologists should be able to definitively and differentially diagnose eye symptoms and pay attention to systemic conditions to provide a series of optimized treatments.

摘要

背景

伴有眼内转移的淋巴瘤是一种罕见且严重的疾病。我们描述了一例伴有虹膜转移的弥漫性大B细胞淋巴瘤（DLBCL）病例。同时，我们参考通过PubMed检索获得的已发表病例报告来总结这种罕见疾病。

病例介绍

一名50岁女性入院时左眼出现青光眼和葡萄膜炎症状。经过治疗和病理检查，其左眼虹膜被诊断为DLBCL。鉴于患者在当地医院的治疗选择不佳，建议进行原发性眼球摘除作为治疗方案。

结论

系统性淋巴瘤的虹膜转移是一种极其罕见的眼科疾病，预后较差。眼科医生应能够明确且鉴别诊断眼部症状，并关注全身状况以提供一系列优化治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3af7/7874580/7b8db1117fad/j_biol-2021-0008-fig007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3af7/7874580/99f4c686aff9/j_biol-2021-0008-fig001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3af7/7874580/777cb28bf77a/j_biol-2021-0008-fig002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3af7/7874580/1cc3c929e78a/j_biol-2021-0008-fig003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3af7/7874580/fef30ae4ca23/j_biol-2021-0008-fig004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3af7/7874580/a55d7cf749d9/j_biol-2021-0008-fig005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3af7/7874580/532cb4cac43a/j_biol-2021-0008-fig006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3af7/7874580/7b8db1117fad/j_biol-2021-0008-fig007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3af7/7874580/99f4c686aff9/j_biol-2021-0008-fig001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3af7/7874580/777cb28bf77a/j_biol-2021-0008-fig002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3af7/7874580/1cc3c929e78a/j_biol-2021-0008-fig003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3af7/7874580/fef30ae4ca23/j_biol-2021-0008-fig004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3af7/7874580/a55d7cf749d9/j_biol-2021-0008-fig005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3af7/7874580/532cb4cac43a/j_biol-2021-0008-fig006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3af7/7874580/7b8db1117fad/j_biol-2021-0008-fig007.jpg

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