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[离子通道病和室性心动过速患者植入式环形记录仪的适应证]

[Indications for implantable loop recorders in patients with channelopathies and ventricular tachycardias].

作者信息

Köbe Julia, Wasmer Kristina, Reinke Florian, Eckardt Lars

机构信息

Abteilung für Rhythmologie, Department für Kardiologie und Angiologie, Universitätsklinikum Münster, Albert-Schweitzer-Campus 1, Gebäude A1, 48149, Münster, Deutschland.

出版信息

Herzschrittmacherther Elektrophysiol. 2016 Dec;27(4):360-365. doi: 10.1007/s00399-016-0474-y.

Abstract

Implantable loop recorders (ILR) do not play a pivotal role in the current guidelines on ventricular arrhythmias except in identifying rhythm-symptom correlations if ventricular arrhythmias are assumed. Before a decision for a pure diagnostic implantable device is made, a thorough arrhythmic risk assessment is of major importance due to the potential lethal outcome of ventricular arrhythmias. Nevertheless, some clinical circumstances exist where long-term monitoring by an ILR may add significant information in electrical heart diseases, in patients with ventricular arrhythmias, or structural heart diseases and a potential risk of ventricular arrhythmias. As medical therapy (β-blocker therapy) plays an important role in long QT syndrome (LQTS) and catecholaminergic polymorphic ventricular tachycardias (cpVT), the ILR can be used to control therapy in patients at risk. In electrical diseases without pharmacologic therapeutic options (e. g., Brugada syndrome), the ILR may be used in low-risk patients with atypical syncope as benign faints may occur without association to the underlying disease. Evidence on cardiomyopathies with preserved left ventricular function and nonsustained VT or premature ventricular complexes is scarce. The ILR may also add long-term information on the individual risk in these circumstances. In very rare diseases like infiltrative disease or muscular dystrophies, the ILR may also provide evidence on risk stratification. In summary, ILR in electrical heart diseases and in patients with ventricular tachycardia remains a very individual decision taking into account various clinical, electrocardiographic, and genetic parameters. The following review aims at highlighting possible indications and clinical scenarios for ILR in ventricular tachycardias and electrical heart diseases with-probably debatable-case presentations.

摘要

植入式循环记录仪(ILR)在当前关于室性心律失常的指南中并不起关键作用,除非假定存在室性心律失常时用于确定节律与症状的相关性。在决定植入单纯诊断性设备之前,由于室性心律失常可能导致致命后果,进行全面的心律失常风险评估至关重要。然而,在某些临床情况下,ILR的长期监测可能会为心脏电疾病、室性心律失常患者、结构性心脏病以及存在室性心律失常潜在风险的患者提供重要信息。由于药物治疗(β受体阻滞剂治疗)在长QT综合征(LQTS)和儿茶酚胺能多形性室性心动过速(cpVT)中起着重要作用,ILR可用于监测有风险患者的治疗情况。在没有药物治疗选择的心脏电疾病(如Brugada综合征)中,ILR可用于低风险的非典型晕厥患者,因为可能会出现与潜在疾病无关的良性晕厥。关于左心室功能保留且有非持续性室性心动过速或室性早搏的心肌病的证据很少。在这些情况下,ILR也可能提供有关个体风险的长期信息。在诸如浸润性疾病或肌肉营养不良等非常罕见的疾病中,ILR也可能为风险分层提供证据。总之,对于心脏电疾病和室性心动过速患者,是否使用ILR仍然是一个非常个体化的决定,需要考虑各种临床、心电图和基因参数。以下综述旨在强调ILR在室性心动过速和心脏电疾病中可能的适应证和临床情况,并伴有可能存在争议的病例介绍。

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