Athappan G, Raza Mohammad Qasim, Kapadia Samir R
Department of Cardiovascular Medicine, Heart & Vascular Institute, Temple University Hospital, 3401 North Broad Street, Philadelphia, PA 19140, USA.
Department of Cardiovascular Medicine, Heart & Vascular Institute, Cleveland Clinic, 9500 Euclid Avenue, J2-3, Cleveland, OH 44195, USA.
Interv Cardiol Clin. 2016 Jan;5(1):71-82. doi: 10.1016/j.iccl.2015.08.006. Epub 2015 Oct 9.
Primary mitral regurgitation (MR) owing to degenerative changes in the structural components of the mitral valve is a common acquired valvular pathology in the elderly. Surgical correction with mitral valve repair (MVRe) or replacement (MVR) is the mainstay of therapy. A significant proportion of patients are ineligible for MVRe/MVR owing to prohibitive surgical risk from advanced age, poor ventricular function, or associated comorbidities. Percutaneous mitral valve repair techniques have been developed to fill this void. The edge-to-edge MitraClip has accrued the largest human experience. This paper reviews the available literature on the MitraClip device for treatment of primary MR.
由于二尖瓣结构成分的退行性改变导致的原发性二尖瓣反流（MR）是老年人常见的后天性瓣膜病变。二尖瓣修复术（MVRe）或置换术（MVR）进行手术矫正 是主要的治疗方法。由于高龄、心室功能差或合并其他疾病导致手术风险过高，相当一部分患者不适合进行MVRe/MVR。经皮二尖瓣修复技术已被开发出来以填补这一空白。缘对缘MitraClip积累了最多的人体应用经验。本文回顾了关于使用MitraClip装置治疗原发性MR的现有文献。
