Crawford Timothy N, Thornton Alice
1 School of Nursing, University of Louisville, Louisville, KY, USA.
2 College of Medicine, University of Kentucky, Lexington, KY, USA.
J Int Assoc Provid AIDS Care. 2017 Jan/Feb;16(1):42-47. doi: 10.1177/2325957416678929. Epub 2016 Nov 16.
To examine the relationship between retention in continuous care and sustained viral suppression.
The authors retrospectively followed 653 persons who were virally suppressed and seeking care at an infectious disease clinic in Kentucky for an average of 6 years to determine the rates of retention in medical care (≥2 visits separated by ≥3 months within a 12-month period) and sustained viral suppression (<400 copies/mL). A generalized linear mixed model was used to determine an association between retention and suppression over time.
Approximately 61% of the study population were retained in continuous care and 75% had sustained viral suppression for all patient-years. Persons retained in care were 3 times the odds of sustaining viral suppression over time ( P < .001).
Retention is essential to achieving and maintaining viral suppression. Strategies should be set in place that emphasize increasing the rates of retention, which in turn may increase the rates of suppression.
探讨持续治疗的留存率与病毒持续抑制之间的关系。
作者对653名病毒得到抑制且在肯塔基州一家传染病诊所接受治疗的患者进行了平均6年的回顾性随访，以确定医疗留存率（在12个月内≥2次就诊，且就诊间隔≥3个月）和病毒持续抑制率（<400拷贝/毫升）。采用广义线性混合模型来确定留存率与随时间推移的病毒抑制之间的关联。
在所有患者年中，约61%的研究人群接受了持续治疗，75%实现了病毒持续抑制。接受治疗的患者随着时间推移实现病毒持续抑制的几率是未接受治疗患者的3倍（P < .001）。
留存率对于实现和维持病毒抑制至关重要。应制定策略以强调提高留存率，这反过来可能会提高病毒抑制率。
