Peterson A V, Marek P M, Mann S L
Department of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98104.
NCI Monogr. 1989(8):63-9.
Questionnaire data obtained from 1,631 tenth grade students in 14 school districts in the State of Washington are used in this investigation of the relationship between the onset processes for smokeless tobacco use and smoking. Emphasized is the use of time-to-event data on the ages of occurrence of six events in these onset processes. Concepts and methods for the statistical analysis of time-to-event data are demonstrated. The occurrence of events in the smoking onset process are strongly related to increases in the subsequent onset rate for smokeless tobacco use. Compared with before initial smoking has occurred, the onset rates for weekly smokeless tobacco use after initial smoking has occurred are 2.03 (P less than .001) and 6.72 (P less than .001) times as large for males and females, respectively. Furthermore, both initial and weekly use of cigarettes contributes to the risk of subsequent weekly smokeless tobacco use. Conversely, the steps in the onset process of smokeless tobacco use are strongly related to increases in the subsequent smoking onset rate. Possible implications for intervention in prevention of smokeless tobacco use and for further research are discussed.
本研究利用从华盛顿州14个学区的1631名十年级学生那里获得的问卷调查数据，来调查无烟烟草使用和吸烟的起始过程之间的关系。重点在于使用这些起始过程中六个事件发生年龄的生存时间数据。展示了生存时间数据统计分析的概念和方法。吸烟起始过程中事件的发生与随后无烟烟草使用起始率的增加密切相关。与初次吸烟发生之前相比，初次吸烟发生之后男性和女性每周无烟烟草使用的起始率分别是之前的2.03倍（P小于0.001）和6.72倍（P小于0.001）。此外，初次和每周吸烟都会增加随后每周无烟烟草使用的风险。相反，无烟烟草使用起始过程中的各个步骤与随后吸烟起始率的增加密切相关。讨论了对预防无烟烟草使用干预措施以及进一步研究可能产生的影响。
