Tongut Aybala, Özyedek Zeki, Çerezci İsmail, Erentürk Selim, Hatemi Ali Can
1 Kartal Kosuyolu Heart Center, Pediatric Cardiovascular Surgery Clinic, Istanbul, Turkey.
2 Maçka Emar Advanced Medical Imaging Center, Istanbul, Turkey.
J Int Med Res. 2016 Dec;44(6):1492-1505. doi: 10.1177/0300060516667118. Epub 2016 Nov 18.
Objective Coronary artery anomaly (CAA) is a remarkable etiological factor for sudden cardiac death in young adults. The incidence of CAA is unknown, with most reliable data available based on postmortem/angiography investigations. This study aimed to assess the prevalence of different forms of coronary anomalies, and to investigate the relationships between demographic data and occurrence of CAA. Methods A total of 2401 consecutive patients (1805 men; mean age, 56 ± 11.7 years), who were referred between January 2005 and December 2008 for noninvasive multi-slice computed tomography (MSCT) imaging, were retrospectively analysed. Results A total of 225 cases (191 men; mean age, 55.9 ± 12) of CAAs were identified (9.37%). Because 11 patients had multiple muscular bridges of the coronary arteries, 236 coronary artery anomalies were found in these 225 patients. Cases were classified into three groups: group 1, coronary anomalies of origin and distribution (n = 36, 1.5%); group 2, anomalies of intrinsic coronary arterial anatomy (n = 180, 7.49%); and group 3, anomalies of coronary termination (n = 9, 0.4%). Conclusion The prevalence of CAA was 9.37% in our single-centre study, which is consistent with previous research. A minimally invasive tool, such as MSCT angiography, should be used to identify CAA.
目的 冠状动脉异常(CAA)是年轻成年人心脏性猝死的一个重要病因。CAA的发病率尚不清楚,最可靠的数据来自尸检/血管造影检查。本研究旨在评估不同形式冠状动脉异常的患病率,并调查人口统计学数据与CAA发生之间的关系。方法 对2005年1月至2008年12月期间因无创多层螺旋CT(MSCT)成像而转诊的2401例连续患者(1805例男性;平均年龄56±11.7岁)进行回顾性分析。结果 共识别出225例CAA病例(191例男性;平均年龄55.9±12岁)(9.37%)。由于11例患者有多处冠状动脉肌桥,在这225例患者中发现了236处冠状动脉异常。病例分为三组:第1组,冠状动脉起源和分布异常(n = 36,1.5%);第2组,冠状动脉内在解剖结构异常(n = 180,7.49%);第3组,冠状动脉终止异常(n = 9,0.4%)。结论 在我们的单中心研究中,CAA的患病率为9.37%,与先前的研究一致。应使用MSCT血管造影等微创工具来识别CAA。