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多层螺旋计算机断层扫描冠状动脉造影显示的先天性冠状动脉异常患病率:来自土耳其的单中心研究

Prevalence of congenital coronary artery anomalies as shown by multi-slice computed tomography coronary angiography: a single-centre study from Turkey.

作者信息

Tongut Aybala, Özyedek Zeki, Çerezci İsmail, Erentürk Selim, Hatemi Ali Can

机构信息

1 Kartal Kosuyolu Heart Center, Pediatric Cardiovascular Surgery Clinic, Istanbul, Turkey.

2 Maçka Emar Advanced Medical Imaging Center, Istanbul, Turkey.

出版信息

J Int Med Res. 2016 Dec;44(6):1492-1505. doi: 10.1177/0300060516667118. Epub 2016 Nov 18.

DOI:10.1177/0300060516667118
PMID:27856928
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5536768/
Abstract

Objective Coronary artery anomaly (CAA) is a remarkable etiological factor for sudden cardiac death in young adults. The incidence of CAA is unknown, with most reliable data available based on postmortem/angiography investigations. This study aimed to assess the prevalence of different forms of coronary anomalies, and to investigate the relationships between demographic data and occurrence of CAA. Methods A total of 2401 consecutive patients (1805 men; mean age, 56 ± 11.7 years), who were referred between January 2005 and December 2008 for noninvasive multi-slice computed tomography (MSCT) imaging, were retrospectively analysed. Results A total of 225 cases (191 men; mean age, 55.9 ± 12) of CAAs were identified (9.37%). Because 11 patients had multiple muscular bridges of the coronary arteries, 236 coronary artery anomalies were found in these 225 patients. Cases were classified into three groups: group 1, coronary anomalies of origin and distribution (n = 36, 1.5%); group 2, anomalies of intrinsic coronary arterial anatomy (n = 180, 7.49%); and group 3, anomalies of coronary termination (n = 9, 0.4%). Conclusion The prevalence of CAA was 9.37% in our single-centre study, which is consistent with previous research. A minimally invasive tool, such as MSCT angiography, should be used to identify CAA.

摘要

目的 冠状动脉异常(CAA)是年轻成年人心脏性猝死的一个重要病因。CAA的发病率尚不清楚,最可靠的数据来自尸检/血管造影检查。本研究旨在评估不同形式冠状动脉异常的患病率,并调查人口统计学数据与CAA发生之间的关系。方法 对2005年1月至2008年12月期间因无创多层螺旋CT(MSCT)成像而转诊的2401例连续患者(1805例男性;平均年龄56±11.7岁)进行回顾性分析。结果 共识别出225例CAA病例(191例男性;平均年龄55.9±12岁)(9.37%)。由于11例患者有多处冠状动脉肌桥,在这225例患者中发现了236处冠状动脉异常。病例分为三组:第1组,冠状动脉起源和分布异常(n = 36,1.5%);第2组,冠状动脉内在解剖结构异常(n = 180,7.49%);第3组,冠状动脉终止异常(n = 9,0.4%)。结论 在我们的单中心研究中,CAA的患病率为9.37%,与先前的研究一致。应使用MSCT血管造影等微创工具来识别CAA。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f80/5536768/377886230388/10.1177_0300060516667118-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f80/5536768/377886230388/10.1177_0300060516667118-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f80/5536768/377886230388/10.1177_0300060516667118-fig1.jpg

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