Mitrea Nicoleta, Mosoiu Daniela, Vosit-Steller Julie, Rogozea Liliana
Department for Fundamental, Prophylactic and Clinical Disciplines, Transylvania University Brasov, Romania.
Department for Medical and Surgical Specialties, Transylvania University Brasov, Romania.
Clujul Med. 2016;89(4):486-492. doi: 10.15386/cjmed-660. Epub 2016 Oct 20.
The increasing number of cancer patients, together with the development of new palliative care services in Romania, warrants the evaluation of nursing strategies meant to improve the level of comfort of patients who are suffering from advanced cancer. The main objective of the study was to evaluate the optimal positioning of the subcutaneous (sc) butterfly, in accordance with its resistance in the insertion tissue, the local complications that may occur, and the evaluation of the time of resistance at the insertion site (puncture) with the daily frequency of injectable opioid administration.
A prospective experimental pilot study was designed and conducted between January and May 2011. Patients admitted to the Hospice Casa Sperantei (Brasov, Romania) with moderate or severe cancer pain, who were receiving subcutaneously opioids, over the age of 18, with normal body index ranging from 18.5 - 22.0, were assigned randomly to one of two groups, after signing the informed consent. In group one, the butterfly was positioned with the needle bevel up - this was considered to be the control group as this modality of inserting the needle is considered standard practice; in group two the butterfly was positioned with the needle bevel down - experimental group. The drugs used for pain relief were sc tramadol for moderate pain and sc morphine for severe pain.
Our research supported the hypothesis that the occurrence of local complications coincides with the decrease of sc butterfly resistance in time at the place of insertion, and the sc butterfly has a higher rate of resistance in time at the insertion site if the frequency of injectable opioids administration is lower (twice per day).
The positioning of the butterflies with the bevel down (experimental group) is associated with a longer resistance in time at the site of insertion, and causes fewer local complications compared to the sc butterflies positioned with the bevel up (control group).
罗马尼亚癌症患者数量不断增加,同时新的姑息治疗服务也在发展,这就需要对旨在提高晚期癌症患者舒适度的护理策略进行评估。本研究的主要目的是根据皮下(sc)蝶形针在插入组织中的阻力、可能出现的局部并发症以及插入部位(穿刺)的阻力时间与每日注射用阿片类药物给药频率的关系,评估其最佳放置方式。
设计并于2011年1月至5月进行了一项前瞻性实验性试点研究。入住罗马尼亚布拉索夫希望之家临终关怀院、患有中度或重度癌痛、接受皮下阿片类药物治疗、年龄在18岁以上、身体指数正常范围为18.5 - 22.0的患者,在签署知情同意书后被随机分为两组。在第一组中,蝶形针以针斜面向上的方式放置——这被视为对照组,因为这种针的插入方式被认为是标准做法;在第二组中,蝶形针以针斜面朝下的方式放置——实验组。用于缓解疼痛的药物,中度疼痛用皮下曲马多,重度疼痛用皮下吗啡。
我们的研究支持这样的假设,即局部并发症的发生与皮下蝶形针在插入部位的阻力随时间下降相一致,并且如果注射用阿片类药物给药频率较低(每天两次),皮下蝶形针在插入部位的阻力随时间的保持率更高。
与针斜面向上放置的皮下蝶形针(对照组)相比,针斜面朝下放置的蝶形针(实验组)在插入部位的阻力保持时间更长,且引起的局部并发症更少。