DeJesus Ramona S, Breitkopf Carmen R, Ebbert Jon O, Rutten Lila J Finney, Jacobson Robert M, Jacobson Debra J, Fan Chun, St Sauver Jennifer
Division of Primary Care Internal Medicine, Department of Medicine, Mayo Clinic, Rochester, MN, USA.
Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
Clin Pract Epidemiol Ment Health. 2016 Oct 31;12:67-74. doi: 10.2174/1745017901612010067. eCollection 2016.
Few large studies have examined correlations between anxiety and body mass index (BMI) by gender or racial groups using clinical data.
This study aimed to determine associations between diagnosed anxiety disorders and BMI, and evaluate whether observed associations varied by demographic characteristics.
Data from the Rochester Epidemiology Project (REP) data linkage system were analyzed to examine associations between anxiety disorders and BMI among adults ages 18-85 residing in Olmsted County, MN in 2009 (n=103,557). Height and weight data were available for 75,958 people (73%). The international classification of underweight, overweight, and obesity by BMI was used.
Population consisted of 56% females, 92.8% White individuals, with median age of 46 years. When adjusted for age, sex, and race, we observed a U-shaped association between anxiety and BMI group. Underweight and obese individuals were more likely to have an anxiety diagnosis compared to normal weight individuals. Stratification by sex yielded a U-shaped association between anxiety and BMI only in women. Stratification by race showed a U-shaped association between anxiety and BMI only in the White population. Anxiety was significantly associated only with obesity in the Black population. Anxiety was not associated with a BMI category in Asian or Hispanic groups. Among elderly group, there is inverse correlation between anxiety and obesity.
Our results suggest that anxiety may have heterogeneous associations with BMI in the population. Further research on potential mechanisms contributing to these findings will help direct efforts in anxiety and obesity management across diverse population groups.
很少有大型研究使用临床数据按性别或种族群体来研究焦虑与体重指数（BMI）之间的相关性。
本研究旨在确定已诊断的焦虑症与BMI之间的关联，并评估观察到的关联是否因人口统计学特征而异。
分析来自罗切斯特流行病学项目（REP）数据链接系统的数据，以研究2009年居住在明尼苏达州奥尔姆斯特德县的18 - 85岁成年人（n = 103,557）中焦虑症与BMI之间的关联。75,958人（73%）有身高和体重数据。使用了根据BMI对体重过轻、超重和肥胖进行的国际分类。
人群中56%为女性，92.8%为白人，中位年龄为46岁。在对年龄、性别和种族进行调整后，我们观察到焦虑与BMI组之间呈U形关联。与正常体重个体相比，体重过轻和肥胖个体更有可能被诊断为焦虑症。按性别分层后，仅在女性中焦虑与BMI之间呈U形关联。按种族分层后，仅在白人人群中焦虑与BMI之间呈U形关联。在黑人人群中，焦虑仅与肥胖显著相关。在亚洲或西班牙裔群体中，焦虑与BMI类别无关。在老年人群体中，焦虑与肥胖之间存在负相关。
我们的结果表明，在人群中焦虑与BMI可能存在异质性关联。对导致这些发现的潜在机制进行进一步研究将有助于指导针对不同人群的焦虑和肥胖管理工作。
