University of Edinburgh, Joseph Black Building, David Brewster Road, Edinburg, EH9 3FJ, UK.
Angew Chem Int Ed Engl. 2016 Dec 5;55(49):15356-15359. doi: 10.1002/anie.201609690. Epub 2016 Nov 11.
An aluminum-catalyzed hydroboration of alkynes using either the commercially available aluminum hydride DIBAL-H or bench-stable Et Al⋅DABCO as the catalyst and H-Bpin as both the boron reagent and stoichiometric hydride source has been developed. Mechanistic studies revealed a unique mode of reactivity in which the reaction is proposed to proceed through hydroalumination and σ-bond metathesis between the resultant alkenyl aluminum species and HBpin, which acts to drive turnover of the catalytic cycle.
开发了一种使用商业上可获得的二异丁基氢化铝（DIBAL-H）或稳定的 EtAl⋅DABCO 作为催化剂，以及 H-Bpin 作为硼试剂和化学计量的氢源的炔烃的铝催化氢化硼反应。机理研究揭示了一种独特的反应性模式，其中反应被提议通过反应性铝物种与 HBpin 之间的氢铝化和 σ 键复分解进行，这有助于驱动催化循环的周转。
