Mallik Atul K, Drzezga Alexander, Minoshima Satoshi
Department of Radiology and Imaging Sciences, School of Medicine, University of Utah, Room: 1A71, 30 North 1900 East, Salt Lake City, UT 84132, USA.
Department of Nuclear Medicine, University Hospital of Cologne, Kerpener Street 62, Cologne 50937, Germany.
PET Clin. 2017 Jan;12(1):119-136. doi: 10.1016/j.cpet.2016.08.003. Epub 2016 Oct 5.
Precision medicine (PM) has been defined as "prevention and treatment strategies that take individual variability into account." Molecular imaging (MI) is an ideally suited tool for PM approaches to neurodegenerative dementia and movement disorders (MD). Here we review PM approaches and discuss how they may be applied to other associated neurodegenerative dementia and MD. With ongoing major therapeutic research initiatives that include the use of molecular imaging, we look forward to established interventions targeted to specific molecular pathophysiology and expect the potential benefit of MI PM approaches in neurodegenerative dementia and MD will only increase.
精准医学（PM）被定义为“考虑个体差异的预防和治疗策略”。分子成像（MI）是用于神经退行性痴呆和运动障碍（MD）的精准医学方法的理想工具。在此，我们回顾精准医学方法，并讨论它们如何应用于其他相关的神经退行性痴呆和运动障碍。随着包括使用分子成像在内的正在进行的重大治疗研究计划，我们期待针对特定分子病理生理学的既定干预措施，并预计分子成像精准医学方法在神经退行性痴呆和运动障碍中的潜在益处只会增加。
