Institut Galien Paris-Sud, CNRS UMR 8612, Univ. Paris-Sud, Université Paris-Saclay, 92290 Châtenay-Malabry, France.
Institut Galien Paris-Sud, CNRS UMR 8612, Univ. Paris-Sud, Université Paris-Saclay, 92290 Châtenay-Malabry, France.
Int J Pharm. 2016 Nov 30;514(1):58-72. doi: 10.1016/j.ijpharm.2016.07.030.
This paper reviews the work carried out on cyclodextrins during some thirty years at the Institut Galien Paris-Sud, UMR CNRS 8612, Université Paris-Sud. It represents the normal evolution of this domain of science and the numerous possibilities of cyclodextrins for being a tool adaptable to the most complex situations. The works which have been carried out concern: the investigation of general characteristics of cyclodextrins and derivatives, the preparation and evaluation of inclusion complexes, the use of cyclodextrins in the preparation of drug delivery systems, the various possibilities offered by cyclodextrins and their derivatives for nanoparticle preparation and finally the use of cyclodextrins for the preparation of biomaterials is evoked.
本文回顾了在巴黎南大学综合理工学院、法国国家科学研究中心联合研究单位 8612、巴黎第十一大学进行的三十年来有关环糊精的工作。它代表了这一科学领域的正常发展以及环糊精在适应最复杂情况的工具方面的众多可能性。已经开展的工作涉及：环糊精及其衍生物的一般特性的研究、包合物的制备和评价、在药物传递系统制备中环糊精的应用、环糊精及其衍生物在纳米粒子制备方面提供的各种可能性以及环糊精在生物材料制备中的应用。
