Li C G
Zhong Xi Yi Jie He Za Zhi. 1989 Feb;9(2):98-9, 70.
The Tripterygium wilfordii (TW) was used to treat experimental allergic encephalomyelitis (EAE) in guinea-pig. The morphological change was observed by using light microscope. Lymphocytic histochemical staining was performed on the spinal cord from EAE in guinea-pig. The results were: The incidence of inflammatory reaction, neuraxial swelling, break and neuronal necrosis in the treatment group was lower than that in the control group (P less than 0.01-0.005); the variation of incidence of neurofibrillar demyelinating in the treatment group was smaller than that in the control group (P less than 0.025). The result of ANAE and ALP staining for lymphocytes in the spinal cord from EAE was T-cell. It showed TW could inhibit the allergic action and decrease tissular injury.
雷公藤用于治疗豚鼠实验性变态反应性脑脊髓炎（EAE）。采用光学显微镜观察形态学变化。对豚鼠EAE脊髓进行淋巴细胞组织化学染色。结果显示：治疗组炎症反应、神经轴肿胀、断裂及神经元坏死的发生率低于对照组（P＜0.01 - 0.005）；治疗组神经原纤维脱髓鞘发生率的变化小于对照组（P＜0.025）。EAE脊髓淋巴细胞的ANAE和ALP染色结果为T细胞。表明雷公藤可抑制变态反应并减轻组织损伤。
