van Iersel J J, Formijne Jonkers H A, Verheijen P M, Broeders I A M J, Heggelman B G F, Sreetharan V, Fütterer J J, Somers I, van der Leest M, Consten E C J
Department of Surgery, Meander Medical Centre, Amersfoort, The Netherlands.
Institute of Technical Medicine, Twente University, Enschede, The Netherlands.
Colorectal Dis. 2017 Jan;19(1):O46-O53. doi: 10.1111/codi.13563.
This study compared the diagnostic capabilities of dynamic magnetic resonance defaecography (D-MRI) with conventional defaecography (CD, reference standard) in patients with symptoms of prolapse of the posterior compartment of the pelvic floor.
Forty-five consecutive patients underwent CD and D-MRI. Outcome measures were the presence or absence of rectocele, enterocele, intussusception, rectal prolapse and the descent of the anorectal junction on straining, measured in millimetres. Cohen's Kappa, sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and the positive and negative likelihood ratio of D-MRI were compared with CD. Cohen's Kappa and Pearson's correlation coefficient were calculated and regression analysis was performed to determine inter-observer agreement.
Forty-one patients were available for analysis. D-MRI underreported rectocele formation with a difference in prevalence (CD 77.8% vs D-MRI 55.6%), mean protrusion (26.4 vs 22.7 mm, P = 0.039) and 11 false negative results, giving a low sensitivity of 0.62 and a NPV of 0.31. For the diagnosis of enterocele, D-MRI was inferior to CD, with five false negative results, giving a low sensitivity of 0.17 and high specificity (1.0) and PPV (1.0). Nine false positive intussusceptions were seen on D-MRI with only two missed.
The accuracy of D-MRI for diagnosing rectocele and enterocele is less than that of CD. D-MRI, however, appears superior to CD in identifying intussusception. D-MRI and CD are complementary imaging techniques in the evaluation of patients with symptoms of prolapse of the posterior compartment.
本研究比较了动态磁共振排粪造影(D-MRI)与传统排粪造影(CD,参考标准)对盆底后份脱垂症状患者的诊断能力。
45例连续患者接受了CD和D-MRI检查。观察指标为是否存在直肠膨出、小肠膨出、肠套叠、直肠脱垂以及用力排便时肛管直肠连接部下降情况,以毫米为单位进行测量。将D-MRI的Cohen's Kappa系数、敏感性、特异性、阳性预测值(PPV)、阴性预测值(NPV)以及阳性和阴性似然比与CD进行比较。计算Cohen's Kappa系数和Pearson相关系数,并进行回归分析以确定观察者间的一致性。
41例患者可供分析。D-MRI对直肠膨出形成的报告不足,患病率存在差异(CD为77.8%,D-MRI为55.6%),平均突出度也不同(26.4对22.7mm,P = 0.039),有11例假阴性结果,敏感性低至0.62,NPV为0.31。对于小肠膨出的诊断,D-MRI不如CD,有5例假阴性结果,敏感性低至0.17,特异性(1.0)和PPV(1.0)高。D-MRI上可见9例假阳性肠套叠,仅漏诊2例。
D-MRI诊断直肠膨出和小肠膨出的准确性低于CD。然而,D-MRI在识别肠套叠方面似乎优于CD。D-MRI和CD是评估盆底后份脱垂症状患者的互补成像技术。