National Bowel Research Centre, Blizard Institute, Queen Mary University of London, London, UK.
Department of Gastroenterology and Hepatology, Mayo College of Medicine, Rochester, MN, USA.
Nat Rev Gastroenterol Hepatol. 2018 May;15(5):309-323. doi: 10.1038/nrgastro.2018.27. Epub 2018 Apr 11.
Faecal incontinence and evacuation disorders are common, impair quality of life and incur substantial economic costs worldwide. As symptoms alone are poor predictors of underlying pathophysiology and aetiology, diagnostic tests of anorectal function could facilitate patient management in those cases that are refractory to conservative therapies. In the past decade, several major technological advances have improved our understanding of anorectal structure, coordination and sensorimotor function. This Consensus Statement provides the reader with an appraisal of the current indications, study performance characteristics, clinical utility, strengths and limitations of the most widely available tests of anorectal structure (ultrasonography and MRI) and function (anorectal manometry, neurophysiological investigations, rectal distension techniques and tests of evacuation, including defecography). Additionally, this article provides our consensus on the clinical relevance of these tests.
粪便失禁和排便障碍较为常见,会降低生活质量并在全球范围内造成巨大的经济负担。由于仅症状并不能很好地预测潜在的病理生理学和病因,因此对肛门直肠功能的诊断性检查可以为那些对保守治疗无反应的患者的管理提供便利。在过去的十年中,几项重大的技术进步提高了我们对肛门直肠结构、协调性和感觉运动功能的理解。本共识声明为读者提供了对最广泛应用的肛门直肠结构(超声和 MRI)和功能(肛门直肠测压、神经生理学研究、直肠扩张技术和排便试验,包括排粪造影)的当前适应证、研究性能特征、临床实用性、优势和局限性的评估。此外,本文还就这些检查的临床相关性达成了共识。