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视力正常的无痛性棘阿米巴角膜炎

Painless Acanthamoeba Keratitis with Normal Vision.

作者信息

Kwok Pui Wai Rachel, Kam Ka Wai, Jhanji Vishal, Young Alvin L

机构信息

*MRCSEd(Ophth), MBBS †MD ‡FRCS, MMedSc(Hons) Department of Ophthalmology & Visual Sciences, Prince of Wales Hospital and Alice Ho Miu Ling Nethersole Hospital, Shatin, New Territory, Hong Kong, SAR (PWRK, KWK, VJ, ALY); and Department of Ophthalmology & Visual Sciences, The Chinese University of Hong Kong, Shatin, New Territory, Hong Kong, SAR (VJ, ALY).

出版信息

Optom Vis Sci. 2017 Mar;94(3):432-435. doi: 10.1097/OPX.0000000000001023.

Abstract

PURPOSE

To report an atypical case of contact lens-related Acanthamoeba keratitis.

CASE REPORT

A 15-year-old secondary school female student with a history of soft contact lens wear was referred to our hospital by a private general practitioner for management of right eye redness and discomfort for 2 weeks. Upon examination, the best-corrected visual acuity was 20/20 and 20/16 for her right and left eyes, respectively. There was diffuse radial keratoneuritis noted in the cornea of her right eye without any associated epithelial defect. Corneal scraping was performed to induce epithelial defect over the keratoneuritis area, and it was positive for Acanthamoeba trophozoites. She was treated with amoebicidal therapy consisting of propamidine isethionate 0.1% and polyhexamethylene biguanide 0.02%, for 6 months. The patient did not complain of any ocular pain in the entire course of her disease. She attained a final visual acuity of 20/13 in the affected eye with residual peripheral radial perineuritic scar.

CONCLUSIONS

Atypical presentation of Acanthamoeba infection is uncommon. This case should arouse the awareness of an indolent presentation of this potentially sight-threatening disease. Clinicians should have a high level of suspicion in contact lens users who present with corneal abnormalities despite an absence of pain. Microbiological work-up and prompt treatment led to a complete resolution of Acanthamoeba infection in our patient.

摘要

目的

报告一例非典型的与隐形眼镜相关的棘阿米巴角膜炎病例。

病例报告

一名15岁的女中学生,有佩戴软性隐形眼镜的病史,因右眼发红和不适2周被一名私人全科医生转诊至我院。检查时,她右眼和左眼的最佳矫正视力分别为20/20和20/16。右眼角膜可见弥漫性放射状角膜神经炎,无相关上皮缺损。在角膜神经炎区域进行角膜刮片以造成上皮缺损,结果显示棘阿米巴滋养体阳性。她接受了为期6个月的由0.1%的依西酸丙脒和0.02%的聚六亚甲基双胍组成的杀阿米巴治疗。在整个病程中,患者未诉任何眼痛。患眼最终视力达到20/13,遗留周边放射状角膜神经炎瘢痕。

结论

棘阿米巴感染的非典型表现并不常见。该病例应引起对这种潜在威胁视力疾病的隐匿性表现的认识。对于出现角膜异常但无疼痛的隐形眼镜使用者,临床医生应高度怀疑。微生物学检查和及时治疗使我们的患者的棘阿米巴感染完全消退。

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