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精神分裂症和代谢综合征患者的感知需求及健康相关生活质量:一项“真实世界”研究。

Perceived needs and health-related quality of life in people with schizophrenia and metabolic syndrome: a "real-world" study.

作者信息

Medeiros-Ferreira Leticia, Navarro-Pastor José Blas, Zúñiga-Lagares Antonio, Romaní Rosanna, Muray Elisenda, Obiols Jordi E

机构信息

Department of Clinical and Health Psychology, Faculty of Psychology, Universitat Autònoma de Barcelona/Nou Barris Nord Mental Health Center, Paseo Valldaura 214- bajos, 08042, Barcelona, Spain.

Nou Barris Nord Mental Health Center, Paseo Valldaura 214- bajos, 08042, Barcelona, Spain.

出版信息

BMC Psychiatry. 2016 Nov 21;16(1):414. doi: 10.1186/s12888-016-1005-4.

Abstract

BACKGROUND

The complexity of schizophrenia lies in the combination of psychiatric, somatic and social needs requiring care. The aim of the study was to compare perceived needs between groups with absence/presence of metabolic syndrome (MetS) and to analyze the relationship between needs, health-related quality of life (HRQoL) and MetS in people with schizophrenia or schizoaffective disorder.

METHODS

A "real-world" cross-sectional study was set up with a comprehensive framework including the following, needs for care (Camberwell Assessment of Need Interview [CAN]), HRQoL (Euro Qol-5D Questionnaire), sociodemographic data, lifestyle habits, psychopathology (Positive And Negative Syndrome Scale [PANSS]), global functioning (Global Assessment of Functioning Scale [GAF]), anthropometric measurements and blood test results were assessed for an outpatient sample (n = 60).

RESULTS

The mean number of needs (given by CAN) was identified for both groups. Patients with MetS rated a higher number of needs compared to the group without this condition. Mobility problems (given by EQ-5D) were negatively associated with the number of total and unmet needs. For participants with MetS, HRQoL was related to the number of needs and unmet needs. For people with MetS, positive symptomatology score (given by PANSS) was related to the number of needs and met needs and general symptomatology was associated with total, met and unmet needs. For individuals without MetS, the global functioning score (given by GAF) was significantly inversely related with total, met and unmet needs.

CONCLUSIONS

Needs and HRQoL, as well as general symptomatology, were related only in patients with MetS. This has implications for treatment planning at the individual and organizational levels. An analysis of both physical and mental needs could provide a starting point for the extension of facilities in the health care system in order to reach the goal of improving quality of life.

摘要

背景

精神分裂症的复杂性在于其精神、躯体和社会护理需求交织在一起。本研究旨在比较存在/不存在代谢综合征(MetS)的两组患者的感知需求,并分析精神分裂症或分裂情感性障碍患者的需求、健康相关生活质量(HRQoL)与MetS之间的关系。

方法

开展了一项“真实世界”横断面研究,采用了一个综合框架,包括护理需求(坎伯韦尔需求评估访谈[CAN])、HRQoL(欧洲五维健康量表问卷)、社会人口统计学数据、生活方式习惯、精神病理学(阳性和阴性症状量表[PANSS])、整体功能(功能总体评定量表[GAF]),对一个门诊样本(n = 60)进行人体测量和血液检查结果评估。

结果

确定了两组患者的平均需求数量(由CAN得出)。与无此病症的组相比,患有MetS的患者列出的需求数量更多。行动问题(由EQ - 5D得出)与总需求和未满足需求的数量呈负相关。对于患有MetS的参与者,HRQoL与需求和未满足需求的数量相关。对于患有MetS的人,阳性症状评分(由PANSS得出)与需求和已满足需求的数量相关,一般症状与总需求、已满足需求和未满足需求相关。对于无MetS的个体,整体功能评分(由GAF得出)与总需求、已满足需求和未满足需求显著负相关。

结论

需求与HRQoL以及一般症状仅在患有MetS的患者中相关。这对个体和组织层面的治疗规划具有启示意义。对身心需求进行分析可为扩大医疗保健系统设施提供一个起点,以实现改善生活质量的目标。

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