Laboratoire de Physiologie Cellulaire et Végétale, UMR5168, Centre National de la Recherche Scientifique, Université Grenoble Alpes, Institut National Recherche Agronomique, Commissariat à l'Energie Atomique et aux Energies Alternatives, BIG, 17 Rue des Martyrs, F-38054 Grenoble, France.
Laboratoire de Physiologie Cellulaire et Végétale, UMR5168, Centre National de la Recherche Scientifique, Université Grenoble Alpes, Institut National Recherche Agronomique, Commissariat à l'Energie Atomique et aux Energies Alternatives, BIG, 17 Rue des Martyrs, F-38054 Grenoble, France.
Prog Lipid Res. 2017 Jan;65:12-23. doi: 10.1016/j.plipres.2016.11.001. Epub 2016 Nov 19.
In plant cells, phosphatidylcholine (PC) is a major glycerolipid of most membranes but practically lacking from the plastid internal membranes. In chloroplasts, PC is absent from the thylakoids and the inner envelope membrane. It is however the main component of the outer envelope membrane, where it exclusively distributes in the outer monolayer. This unique distribution is likely related with operational compartmentalization of plant lipid metabolism. In this review, we summarize the different mechanisms involved in homeostasis of PC in plant cells. The specific origin of chloroplast PC is examined and the involvement of the P4-ATPase family of phospholipid flippases (ALA) is considered with a special attention to the recently reported effect of the endoplasmic reticulum-localized ALA10 on modification of chloroplast PC desaturation. The different possible roles of chloroplast PC are then discussed and analyzed in consideration of plant physiology.
在植物细胞中，磷脂酰胆碱 (PC) 是大多数膜的主要甘油磷脂，但实际上不存在于质体内部膜中。在叶绿体中，PC 不存在于类囊体和内囊膜中。然而，它是外囊膜的主要成分，仅分布在外层单层中。这种独特的分布可能与植物脂类代谢的功能分区化有关。在这篇综述中，我们总结了植物细胞中 PC 动态平衡所涉及的不同机制。我们考察了叶绿体 PC 的特定来源，并考虑了 P4-ATPase 家族的磷脂翻转酶（ALA）的作用，特别关注最近报道的内质网定位的 ALA10 对叶绿体 PC 去饱和修饰的影响。然后，我们考虑了植物生理学，讨论并分析了叶绿体 PC 的不同可能作用。
