Sofianos Chrysis, Chauke Nkhensani Y, Grubnik Alexandra
Department of Plastic and Reconstructive Surgery, University of the Witwatersrand, Johannesburg, South Africa.
BMJ Case Rep. 2016 Nov 21;2016:bcr2016217661. doi: 10.1136/bcr-2016-217661.
Trichilemmal carcinoma (TC) is described as a very rare cancer of the skin adnexa. Ninety per cent of the lesions present on the scalp. Prognostic factors in TC are limited to lymph node status and surgical margins, with no statistical significance observed for age or gender of the patient, size of tumour or locoregional recurrence. We present a 46-year-old black patient who developed TC during treatment for breast cancer. Postoperative histology of the scalp lesion excision confirmed no involved margins. At the three monthly appointment, the patient was reviewed and multiple, new scalp lesions were noted. A CT scan of the head, neck found multiple lesions on the scalp, limited to the soft tissue, not involving the outer table of the skull. There was bilateral invasion of the parotid glands. To the best of our knowledge, no syndromes or associations between breast cancer and adnexal skin tumours exist.
外毛根鞘癌（TC）被描述为一种非常罕见的皮肤附属器癌症。90%的病变出现在头皮上。外毛根鞘癌的预后因素仅限于淋巴结状态和手术切缘，患者的年龄、性别、肿瘤大小或局部区域复发均无统计学意义。我们报告一名46岁的黑人患者，其在乳腺癌治疗期间发生了外毛根鞘癌。头皮病变切除术后的组织学检查证实切缘无肿瘤累及。在三个月一次的复诊时，对患者进行了检查，发现头皮上有多个新病变。头部和颈部的CT扫描发现头皮上有多个病变，局限于软组织，未累及颅骨外板。双侧腮腺受侵。据我们所知，乳腺癌与附属器皮肤肿瘤之间不存在综合征或关联。
