Hiramatsu K, Sasaki K, Matsuda M, Hashimoto M, Eguchi T, Tomikawa S, Fujii T, Watanabe G
Department of Digestive Surgery, Hepatopancreatobiliary Surgery Unit, Toranomon Hospital, Tokyo, Japan.
Department of Digestive Surgery, Hepatopancreatobiliary Surgery Unit, Toranomon Hospital, Tokyo, Japan.
Transplant Proc. 2015 Jan-Feb;47(1):155-7. doi: 10.1016/j.transproceed.2014.10.015.
Transplant recipients receiving immunosuppressants are at a high risk of cancer, especially skin cancer. Trichilemmal carcinoma is comparatively rare compared with other skin cancers. We report here a first case of trichilemmal carcinoma arising in a kidney transplant recipient. A 63-year-old man who had undergone a living donor renal transplantation at the age of 50 years presented with a 15 × 10 mm lesion on his forehead. The pathological diagnosis after resection was trichilemmal carcinoma. Distant metastases involving the lymph nodes, lung, and liver occurred, and the patient died. Given that trichilemmal carcinoma generally has an indolent clinical course and a low metastatic potential, the present case of trichilemmal carcinoma with an aggressive course resulting in distant metastases is rare.
接受免疫抑制剂治疗的移植受者患癌症的风险很高，尤其是皮肤癌。与其他皮肤癌相比，毛发上皮瘤相对罕见。我们在此报告首例发生于肾移植受者的毛发上皮瘤。一名63岁男性，50岁时接受了活体供肾移植，前额出现一个15×10毫米的病变。切除后的病理诊断为毛发上皮瘤。发生了远处转移，累及淋巴结、肺和肝脏，患者死亡。鉴于毛发上皮瘤通常临床病程较为惰性且转移潜能较低，本例具有侵袭性病程并导致远处转移的毛发上皮瘤十分罕见。
