Chon Joon Woo, Lee Ji Yun, Song Yoon Ju, Kim Jin Hwan, Chung Dong June
Department of Polymer Science and Engineering, Sungkyunkwan University, Suwon, 16419 Korea.
M&B GreenUs Co, Ltd, #1016, 278, Beotkkot-ro, Geumcheon-gu, Seoul 08511 Korea.
Biomater Res. 2016 Nov 14;20:35. doi: 10.1186/s40824-016-0082-2. eCollection 2016.
In this study, cytotoxicity of various novel poly(alkylpehnol) derivatives which, one of constituent for vulcanizing agent, could be adjusted in medical elastic rubber applications were investigated under various conditions of cytotoxicity test. By MTT-assay which according to ISO 10993-5 regulation, we could figure out cell viability of mouse fibroblast in various sample conditions. Furthermore, by Live & Dead Cell assay, we could get colorimetric cell viability via fluorescence images.
在本研究中,在细胞毒性测试的各种条件下,研究了作为硫化剂成分之一的各种新型聚(烷基苯酚)衍生物在医用弹性橡胶应用中的细胞毒性可调节性。通过根据ISO 10993-5规定的MTT测定法,我们可以确定在各种样品条件下小鼠成纤维细胞的细胞活力。此外,通过活细胞与死细胞测定法,我们可以通过荧光图像获得比色法细胞活力。