Moschcovich Laura, Kessler Efrat
Maurice and Gabriela Goldschleger Eye Research Institute, Tel-Aviv University Sackler Faculty of Medicine, Sheba Medical Center, Tel-Hashomer 52621, Israel.
Data Brief. 2016 Nov 3;9:883-887. doi: 10.1016/j.dib.2016.10.027. eCollection 2016 Dec.
This article provides kinetic constants for C-terminal processing of procollagen type I by bone morphogenetic protein 1 (BMP-1; the major procollagen C-proteinase), a reaction stimulated by the connective tissue glycoprotein procollagen C-proteinase enhancer 1 (PCPE-1). Reported are , , and / (catalytic coefficient) values for BMP-1 alone, BMP-1 with intact PCPE-1, BMP-1 with the CUB (Complement C1r/C1s, Uegf, BMP-1) domains fragment of PCPE-1 as well as its NTR (netrin-like) domain.
本文提供了骨形态发生蛋白1(BMP-1;主要的前胶原C蛋白酶)对I型前胶原进行C端加工的动力学常数,该反应由结缔组织糖蛋白前胶原C蛋白酶增强子1(PCPE-1)刺激。报告了单独的BMP-1、带有完整PCPE-1的BMP-1、带有PCPE-1的CUB(补体C1r/C1s、Uegf、BMP-1)结构域片段及其NTR(类netrin)结构域的BMP-1的 、 、 以及 /(催化系数)值。