Antti-Poika M, Ojala M, Matikainen E, Vaheri E, Juntunen J
Institute of Occupational Health, Helsinki, Finland.
Int Arch Occup Environ Health. 1989;61(6):397-401. doi: 10.1007/BF00381031.
Forty-eight persons (age 44, SD 9 years) exposed to paint solvents and 40 nonexposed referents (age 45, SD 9 years) were examined. The duration of exposure was 4 to 30 (mean 20) years and the life-time exposure level was estimated to have been 10 to 330 (mean 60%) of the hygienic standard. The methods used were a neurological examination, electroencephalography, brainstem auditory-evoked potentials, electronystagmography, and posturography. Life-time exposure was estimated on the basis of a detailed occupational history and environmental measurements made at the work places over several years. The average weekly alcohol consumption was established in a detailed interview. Due to the small number of subjects examined, the study was inconclusive. The findings classified as abnormal were slightly more common in the exposed than in the referents, and in the persons who used alcohol than in the non-users. The differences were not statistically significant, and no exposure-response relationships were found.
对48名接触油漆溶剂的人员（年龄44岁，标准差9岁）和40名未接触的对照人员（年龄45岁，标准差9岁）进行了检查。接触时长为4至30年（平均20年），终生接触水平估计为卫生标准的10%至330%（平均60%）。所采用的方法包括神经学检查、脑电图、脑干听觉诱发电位、眼震电图和姿势描记法。终生接触情况是根据详细的职业史以及多年来在工作场所进行的环境测量来估计的。通过详细访谈确定了平均每周饮酒量。由于检查的受试者数量较少，该研究没有得出明确结论。被归类为异常的发现，在接触组中比在对照组中略为常见，在饮酒者中比在不饮酒者中略为常见。这些差异无统计学意义，也未发现接触-反应关系。
