Mueller Claudia M, Sinclair Tiffany J, Stevens Megan, Esquivel Micaela, Gordon Noah
Division of Pediatric Surgery, Stanford University School of Medicine, 300 Pasteur Drive, Alway Building M116, MC: 5733, Stanford, CA, 94305, USA.
Department of Anesthesiology, California Pacific Medical Center, 3700 California Street, San Francisco, CA, 94118, USA.
Pediatr Surg Int. 2017 Mar;33(3):341-345. doi: 10.1007/s00383-016-4027-6. Epub 2016 Nov 21.
The use of general anesthesia in young children has come under increasing scrutiny due to its potential long-term neurotoxic effects. Meanwhile, regional anesthesia for surgical procedures in neonates has many advantages, including preservation of respiratory status and faster return to feeding. We describe the successful use of 3% 2-chloroprocaine administered via continuous caudal infusion as the sole anesthetic agent during elective surgical procedures in infants.
A retrospective chart review of all patients who underwent elective surgical procedures under continuous caudal regional anesthetic at a single institution was performed. Thirty patients (27 males, three females) were identified: 28 patients underwent inguinal hernia repairs. Caudal anesthesia was established via continuous infusion of 3% 2-chloroprocaine through an indwelling catheter.
Successful analgesia by regional block alone was achieved in all patients for the duration of each surgical procedure without need for rescue anesthesia. Mean operative time was 49 min. Patients were able to return to feeding immediately after surgery and were ready for discharge home within that day.
Continuous caudal infusion of chloroprocaine is a safe and effective way to maintain adequate analgesia for elective surgeries in infants. This successful regional approach obviates the use of general anesthetic which reduces post-operative recovery time and avoids concerns for neurotoxicity.
由于全身麻醉可能存在长期神经毒性作用,其在幼儿中的使用受到了越来越多的审视。与此同时,新生儿手术的区域麻醉有诸多优点,包括维持呼吸状态以及更快恢复进食。我们描述了在婴儿择期手术过程中,通过持续骶管输注3%氯普鲁卡因作为唯一麻醉剂的成功应用。
对在单一机构接受连续骶管区域麻醉下择期手术的所有患者进行回顾性病历审查。确定了30例患者(27例男性,3例女性):28例患者接受腹股沟疝修补术。通过留置导管持续输注3%氯普鲁卡因建立骶管麻醉。
所有患者在每个手术过程中仅通过区域阻滞就成功实现了镇痛,无需补救麻醉。平均手术时间为49分钟。患者术后能够立即恢复进食,并在当天即可准备出院。
持续骶管输注氯普鲁卡因是维持婴儿择期手术充分镇痛的一种安全有效的方法。这种成功的区域麻醉方法避免了全身麻醉的使用,减少了术后恢复时间,并消除了对神经毒性的担忧。