大建中汤对右侧结肠癌患者术后肠道动力的影响。
The effect of Daikenchuto on postoperative intestinal motility in patients with right-side colon cancer.
作者信息
Yamada Takeshi, Matsumoto Satoshi, Matsuda Michihiro Koizumi Akihisa, Shinji Seiichi, Yokoyama Yasuyuki, Takahashi Goro, Iwai Takuma, Takeda Kouki, Ohta Keiichiro, Uchida Eiji
机构信息
Department of Digestive Surgery, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo, 113-8603, Japan.
出版信息
Surg Today. 2017 Jul;47(7):865-871. doi: 10.1007/s00595-016-1449-7. Epub 2016 Nov 21.
PURPOSE
Daikenchuto (DKT) has a stimulant effect on intestinal motility and reportedly has a positive effect on postoperative intestinal motility in patients with sigmoid colon cancer. In this study, we investigated the effects of DKT in patients with right-side colon cancer.
METHODS
This retrospective study included 88 patients with right-side colon cancer. We orally administered 7.5 g of DKT in the DKT group and did not administer any DKT to patients in the no-DKT group. All patients ingested radiopaque markers 2 h before surgery, which were used to assess intestinal motility. The postoperative intestinal motility was radiologically assessed by counting the numbers of residual markers in the large and small intestines.
RESULTS
The DKT and no-DKT groups showed no marked differences in the total number of residual markers or number of residual markers in the small intestine. However, in the elderly subgroup, the total number of residual markers in the DKT group was significantly less than in the no-DKT group.
CONCLUSION
Although DKT had some small effect on the postoperative intestinal motility for most patients, it may have positive effects in elderly patients.
目的
大建中汤（DKT）对肠道蠕动有刺激作用，据报道对乙状结肠癌患者的术后肠道蠕动有积极影响。在本研究中，我们调查了DKT对右侧结肠癌患者的影响。
方法
这项回顾性研究纳入了88例右侧结肠癌患者。DKT组患者口服7.5克DKT，非DKT组患者不给予任何DKT。所有患者在手术前2小时摄入不透X线标志物，用于评估肠道蠕动。术后通过计算大肠和小肠中残留标志物的数量对肠道蠕动进行放射学评估。
结果
DKT组和非DKT组在残留标志物总数或小肠中残留标志物数量上无明显差异。然而，在老年亚组中，DKT组的残留标志物总数显著少于非DKT组。
结论
虽然DKT对大多数患者的术后肠道蠕动有一些轻微影响，但它可能对老年患者有积极作用。
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