在初级保健中使用认知筛查测试来检测痴呆症和轻度认知障碍的成本效益。
Cost effectiveness of using cognitive screening tests for detecting dementia and mild cognitive impairment in primary care.
机构信息
School of Health and Related Research, University of Sheffield, Sheffield, UK.
Centre for Primary Care, University of Manchester, Manchester, UK.
出版信息
Int J Geriatr Psychiatry. 2017 Dec;32(12):1392-1400. doi: 10.1002/gps.4626. Epub 2016 Nov 22.
INTRODUCTION
We estimated the cost effectiveness of different cognitive screening tests for use by General Practitioners (GPs) to detect cognitive impairment in England.
METHODS
A patient-level cost-effectiveness model was developed using a simulated cohort that represents the elderly population in England (65 years and older). Each patient was followed over a lifetime period. Data from published sources were used to populate the model. The costs include government funded health and social care, private social care and informal care. Patient health benefit was measured and valued in Quality Adjusted Life Years (QALYs).
RESULTS
Base-case analyses found that adopting any of the three cognitive tests (Mini-Mental State Examination, 6-Item Cognitive Impairment Test or GPCOG (General Practitioner Assessment of Cognition)) delivered more QALYs for patients over their lifetime and made savings across sectors including healthcare, social care and informal care compared with GP unassisted judgement. The benefits were due to early access to medications. Among the three cognitive tests, adopting the GPCOG was considered the most cost-effective option with the highest Incremental Net Benefit (INB) at the threshold of £30 000 per QALY from both the National Health Service and Personal Social Service (NHS PSS) perspective (£195 034 per 1000 patients) and the broader perspective that includes private social care and informal care (£196 251 per 1000 patients). Uncertainty was assessed in both deterministic and probabilistic sensitivity analyses.
CONCLUSIONS
Our analyses indicate that the use of any of the three cognitive tests could be considered a cost-effective strategy compared with GP unassisted judgement. The most cost-effective option in the base-case was the GPCOG. Copyright © 2016 John Wiley & Sons, Ltd.
简介
我们评估了普通科医生(GP)使用不同认知筛查测试来检测英格兰认知障碍的成本效益。
方法
采用代表英格兰老年人口(65 岁及以上)的模拟队列,建立了一个患者层面的成本效益模型。每个患者都在一生中进行随访。使用来自已发表来源的数据来填充模型。成本包括政府资助的医疗和社会保健、私人社会保健和非正式护理。患者健康效益以质量调整生命年(QALYs)衡量和估值。
结果
基础案例分析发现,采用任何三种认知测试(简易精神状态检查、6 项认知障碍测试或 GPCOG(全科医生认知评估))都可以使患者在一生中获得更多的 QALYs,并且在医疗保健、社会保健和非正式护理等各个领域都有节省,与 GP 非辅助判断相比。这些好处归因于早期获得药物治疗。在这三种认知测试中,采用 GPCOG 被认为是最具成本效益的选择,在 NHS PSS(国民保健服务和个人社会服务)和包括私人社会保健和非正式护理的更广泛视角下,每增加一个 QALY 的增量净效益(INB)均为 30000 英镑,从 NHS PSS 角度(每 1000 名患者为 195034 英镑)和更广泛的视角(包括私人社会保健和非正式护理)来看,每 1000 名患者为 196251 英镑。在确定性和概率敏感性分析中都评估了不确定性。
结论
我们的分析表明,与 GP 非辅助判断相比,使用这三种认知测试中的任何一种都可以被认为是一种具有成本效益的策略。在基础案例中,最具成本效益的选择是 GPCOG。版权所有©2016 约翰威立父子公司