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输尿管支架置入术与输尿管切开术治疗良性输尿管梗阻猫的疗效比较

Outcome in cats with benign ureteral obstructions treated by means of ureteral stenting versus ureterotomy.

作者信息

Culp William T N, Palm Carrie A, Hsueh Christine, Mayhew Philipp D, Hunt Geraldine B, Johnson Eric G, Drobatz Kenneth J

出版信息

J Am Vet Med Assoc. 2016 Dec 1;249(11):1292-1300. doi: 10.2460/javma.249.11.1292.

DOI:10.2460/javma.249.11.1292
PMID:27875083
Abstract

OBJECTIVE To evaluate the outcome for cats with benign ureteral obstructions treated by means of ureteral stenting and to compare the outcome for these cats with outcome for a historical cohort of cats treated by means of ureterotomy only. DESIGN Prospective study with historical cohort. ANIMALS 62 client-owned cats with benign ureteral obstructions, including 26 cats treated with ureteral stenting and 36 cats previously treated with ureterotomy. PROCEDURES Data were recorded prospectively (ureteral stent cases) or collected retrospectively from the medical records (ureterotomy cases), and results were compared. RESULTS Cats treated with ureteral stents had significantly greater decreases in BUN and serum creatinine concentrations 1 day after surgery and at hospital discharge, compared with values for cats that underwent ureterotomy. Six cats in the ureteral stent group developed abdominal effusion after surgery, and cats in this group were significantly more likely to develop abdominal effusion when a ureterotomy was performed than when it was not. Cats that developed abdominal effusion after surgery were significantly less likely to survive to hospital discharge. Cats that underwent ureteral stenting were significantly more likely to have resolution of azotemia prior to hospital discharge than were cats that underwent ureterotomy alone. CONCLUSIONS AND CLINICAL RELEVANCE Results suggested that cats with benign ureteral obstructions treated with ureteral stenting were more likely to have resolution of azotemia prior to hospital discharge, compared with cats undergoing ureterotomy alone. Results of ureteral stenting were encouraging, but further investigation is warranted.

摘要

目的 评估采用输尿管支架置入术治疗的良性输尿管梗阻猫的预后,并将这些猫的预后与仅接受输尿管切开术治疗的历史队列猫的预后进行比较。 设计 前瞻性研究与历史队列研究。 动物 62只客户拥有的良性输尿管梗阻猫,其中26只接受输尿管支架置入术治疗,36只先前接受输尿管切开术治疗。 程序 前瞻性记录数据(输尿管支架置入术病例)或从病历中回顾性收集数据(输尿管切开术病例),并比较结果。 结果 与接受输尿管切开术的猫相比,接受输尿管支架置入术治疗的猫在术后1天和出院时血尿素氮(BUN)和血清肌酐浓度的下降幅度明显更大。输尿管支架置入术组有6只猫术后出现腹腔积液,该组猫在进行输尿管切开术时比未进行时更易出现腹腔积液。术后出现腹腔积液的猫存活至出院的可能性明显降低。与仅接受输尿管切开术的猫相比,接受输尿管支架置入术的猫在出院前氮质血症缓解的可能性明显更高。 结论及临床意义 结果表明,与仅接受输尿管切开术的猫相比,采用输尿管支架置入术治疗的良性输尿管梗阻猫在出院前氮质血症缓解的可能性更大。输尿管支架置入术的结果令人鼓舞,但仍需进一步研究。

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