Fernando S, McNeil R, Closson K, Samji H, Kirkland S, Strike C, Turje R Baltzer, Zhang W, Hogg R S, Parashar S
British Columbia Centre for Excellence in HIV/AIDS, St. Paul's Hospital, 608-1081 Burrard Street, Vancouver, BC, V6Z 1Y6, Canada.
Faculty of Health Science, Simon Fraser University, Burnaby, Canada.
Harm Reduct J. 2016 Nov 22;13(1):31. doi: 10.1186/s12954-016-0121-2.
People living with HIV (PLHIV) who are also marginalized by social and structural inequities often face barriers to accessing and adhering to HIV treatment and care. The Dr. Peter Centre (DPC) is a non-profit integrated care facility with a supervised injection room that serves PLHIV experiencing multiple barriers to social and health services in Vancouver, Canada. This study examines whether the DPC is successful in drawing in PLHIV with complex health issues, including addiction.
Using data collected by the Longitudinal Investigations into Supportive and Ancillary health services (LISA) study from July 2007 to January 2010, linked with clinical variables available through the British Columbia Centre for Excellence in HIV/AIDS Drug Treatment Program, we identified DPC and non-DPC clients with a history of injection drug use. Bivariable and multivariable logistic regression analyses compared socio-demographic and clinical characteristics of DPC clients (n = 76) and non-DPC clients (n = 482) with a history of injection drug use.
Of the 917 LISA participants included within this analysis, 100 (10.9%) reported being a DPC client, of which 76 reported a history of injection drug use. Adjusted results found that compared to non-DPC clients with a history of injection drug use, DPC-clients were more likely to be male (AOR: 4.18, 95% CI = 2.09-8.37); use supportive services daily vs. less than daily (AOR: 3.16, 95% CI = 1.79-5.61); to have been diagnosed with a mental health disorder (AOR: 2.11; 95% CI: 1.12-3.99); to have a history of interpersonal violence (AOR: 2.76; 95% CI: 1.23-6.19); and to have ever experienced ART interruption longer than 1 year (AOR: 2.39; 95% CI: 1.38-4.15).
Our analyses suggest that the DPC operating care model engages PLHIV with complex care needs, highlighting that integrated care facilities are needed to support the multiple intersecting vulnerabilities faced by PLHIV with a history of injection drug use living within urban centres in North America and beyond.
感染艾滋病毒(PLHIV)的人群若同时因社会和结构不平等而被边缘化,在获取和坚持接受艾滋病毒治疗及护理方面往往面临障碍。彼得医生中心(DPC)是一家非营利性综合护理机构,设有一个监督注射室,为加拿大温哥华在社会和医疗服务方面面临多重障碍的艾滋病毒感染者提供服务。本研究探讨DPC是否成功吸引了有包括成瘾在内的复杂健康问题的艾滋病毒感染者。
利用纵向支持性和辅助性健康服务调查(LISA)研究在2007年7月至2010年1月期间收集的数据,并结合通过不列颠哥伦比亚卓越艾滋病毒/艾滋病药物治疗项目可获取的临床变量,我们确定了有注射吸毒史的DPC客户和非DPC客户。双变量和多变量逻辑回归分析比较了有注射吸毒史的DPC客户(n = 76)和非DPC客户(n = 482)的社会人口统计学和临床特征。
在本次分析纳入的917名LISA参与者中,100人(10.9%)报告是DPC客户,其中76人报告有注射吸毒史。调整后的结果发现,与有注射吸毒史的非DPC客户相比,DPC客户更可能为男性(调整后比值比:4.18,95%置信区间 = 2.09 - 8.37);每天使用支持性服务而非少于每天使用(调整后比值比:3.16,95%置信区间 = 1.79 - 5.61);被诊断患有精神健康障碍(调整后比值比:2.11;95%置信区间:1.12 - 3.99);有人际暴力史(调整后比值比:2.76;95%置信区间:1.23 - 6.19);以及曾经历抗逆转录病毒治疗中断超过1年(调整后比值比:2.39;95%置信区间:1.38 - 4.15)。
我们的分析表明,DPC的运营护理模式吸引了有复杂护理需求的艾滋病毒感染者,这突出表明需要综合护理设施来支持北美及其他地区城市中心有注射吸毒史的艾滋病毒感染者所面临的多重交叉脆弱性。