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加拿大针对注射吸毒人群的传染病预防和管理的健康计划和服务:系统综合评价。

Health programmes and services addressing the prevention and management of infectious diseases in people who inject drugs in Canada: a systematic integrative review.

机构信息

Department of Global Health, McMaster University, Hamilton, Ontario, Canada

Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada.

出版信息

BMJ Open. 2021 Sep 23;11(9):e047511. doi: 10.1136/bmjopen-2020-047511.

Abstract

OBJECTIVES

People who inject drugs (PWID) experience a high burden of injection drug use-related infectious disease and challenges in accessing adequate care. This study sought to identify programmes and services in Canada addressing the prevention and management of infectious disease in PWID.

DESIGN

This study employed a systematic integrative review methodology. Electronic databases (PubMed, CINAHL and Web of Science Core Collection) and relevant websites were searched for literature published between 2008 and 2019 (last search date was 6 June 2019). Eligible articles and documents were required to address injection or intravenous drug use and health programmes or services relating to the prevention or management of infectious diseases in Canada.

RESULTS

This study identified 1607 unique articles and 97 were included in this study. The health programmes and services identified included testing and management of HIV and hepatitis C virus (n=27), supervised injection facilities (n=19), medication treatment for opioid use disorder (n=12), integrated infectious disease and addiction programmes (n=10), needle exchange programmes (n=9), harm reduction strategies broadly (n=6), mobile care initiatives (n=5), peer-delivered services (n=3), management of IDU-related bacterial infections (n=2) and others (n=4). Key implications for policy, practice and future research were identified based on the results of the included studies, which include addressing individual and systemic factors that impede care, furthering evaluation of programmes and the need to provide comprehensive care to PWID, involving medical care, social support and harm reduction.

CONCLUSIONS

These results demonstrate the need for expanded services across a variety of settings and populations. Our study emphasises the importance of addressing social and structural factors that impede infectious disease care for PWID. Further research is needed to improve evaluation of health programmes and services and contextual factors surrounding accessing services or returning to care.

PROSPERO REGISTRATION NUMBER

CRD42020142947.

摘要

目的

注射吸毒者(PWID)面临着较高的与注射吸毒相关的传染病负担,并且在获得足够的护理方面存在挑战。本研究旨在确定加拿大在预防和管理 PWID 感染性疾病方面的各种方案和服务。

方法

本研究采用系统综合评价方法。电子数据库(PubMed、CINAHL 和 Web of Science 核心合集)和相关网站被检索,以获取 2008 年至 2019 年期间发表的文献(最后检索日期为 2019 年 6 月 6 日)。合格的文章和文件必须涉及注射或静脉内药物使用以及与加拿大预防或管理传染病相关的健康方案或服务。

结果

本研究共识别出 1607 篇独特的文章,其中 97 篇被纳入本研究。确定的健康方案和服务包括 HIV 和丙型肝炎病毒的检测和管理(n=27)、监督注射设施(n=19)、阿片类药物使用障碍的药物治疗(n=12)、感染病和成瘾综合方案(n=10)、针具交换方案(n=9)、广泛的减少伤害策略(n=6)、移动护理倡议(n=5)、同伴提供的服务(n=3)、管理 IDU 相关细菌感染(n=2)和其他(n=4)。根据纳入研究的结果,确定了对政策、实践和未来研究的主要影响,其中包括解决妨碍护理的个人和系统因素、进一步评估方案以及向 PWID 提供全面护理的必要性,包括医疗保健、社会支持和减少伤害。

结论

这些结果表明需要在各种环境和人群中扩大服务。我们的研究强调了解决妨碍 PWID 传染病护理的社会和结构性因素的重要性。需要进一步研究以改进健康方案和服务的评估以及在获取服务或重新接受护理方面的背景因素。

登记号

CRD42020142947。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/219a/8461723/6ffe83ec4bf7/bmjopen-2020-047511f01.jpg

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