From the *Department of Nuclear Medicine, Royal Brisbane and Women's Hospital, Herston, Queensland; †School of Medicine, University of Queensland, Brisbane, Queensland; ‡Royal Brisbane and Women's Hospital, Herston; §Department of Anatomical Pathology, Pathology Queensland, Princess Alexandra Hospital, Woolloongabba, Queensland; ∥Department of Medical Imaging, Royal Brisbane and Women's Hospital, Herston, Queensland; and ¶Herston Imaging Research Facility, Brisbane, Queensland, Australia.
Clin Nucl Med. 2017 Feb;42(2):147-148. doi: 10.1097/RLU.0000000000001460.
We report a case of benign senile seminal vesicle amyloidosis demonstrating intense Ga-prostate-specific membrane antigen (PSMA) uptake on PET/CT. A 68-year-old man underwent staging PSMA PET/CT and MRI for biopsy-proven prostate adenocarcinoma. There was an intense focus of Ga-PSMA uptake in the primary malignancy, as well as symmetrical intense uptake in the seminal vesicles bilaterally that was reported as multifocal disease with local invasion. Final histology after radical prostatectomy showed amyloidosis of the seminal vesicles without any evidence of prostate cancer. Care should be taken in the interpretation of seminal vesicle PSMA uptake to avoid overstaging.
我们报告了一例良性老年精囊腺淀粉样变性病例，其在 PET/CT 上显示出强烈的 Ga-前列腺特异性膜抗原（PSMA）摄取。一名 68 岁男性因活检证实的前列腺腺癌进行了分期 PSMA PET/CT 和 MRI。原发性恶性肿瘤中存在 Ga-PSMA 摄取的强烈焦点，以及双侧精囊的对称强烈摄取，报告为多灶性疾病伴局部侵犯。根治性前列腺切除术后的最终组织学检查显示精囊淀粉样变性，没有任何前列腺癌的证据。在解释精囊 PSMA 摄取时应谨慎，以避免过度分期。
