Larsen M J, Kirkegaard E, Poulsen S, Fejerskov O
Department of Oral Anatomy, Royal Dental College, Aarhus, Denmark.
Community Dent Oral Epidemiol. 1989 Aug;17(4):204-6. doi: 10.1111/j.1600-0528.1989.tb00612.x.
The aim of the present study was to describe the intraoral pattern of dental fluorosis among fluoride tablet consumers. One hundred and forty-two children, of whom 56 had participated in a fluoride tablet program of 0.5/1.0 mg NaF per day were examined blindly for possible fluoride-induced enamel changes. A low prevalence of dental fluorosis was found among non-participants. The later in life the tooth was formed, the higher was the prevalence. The subjects who had participated in the fluoride tablet program showed a significantly higher prevalence of fluorosis. They could be divided into three groups: Group 1 exhibited a tooth prevalence pattern not statistically different from that of the non-participants, group 2 showed dental fluorosis in almost all teeth except in those formed before the start of the tablet program. In group 3 the early and the late formed teeth showed very little fluorosis while those formed in the few years just after the initiation of the fluoride tablet intake were affected by fluorosis.
本研究的目的是描述服用氟化物片剂人群的口腔内氟斑牙模式。142名儿童接受了盲法检查,以确定是否存在可能由氟化物导致的釉质变化,其中56名儿童参与了每日服用0.5/1.0毫克氟化钠的氟化物片剂项目。在未参与者中发现氟斑牙的患病率较低。牙齿形成的时间越晚,患病率越高。参与氟化物片剂项目的受试者氟斑牙患病率显著更高。他们可分为三组:第1组的牙齿患病率模式与未参与者无统计学差异,第2组除了在片剂项目开始前形成的牙齿外,几乎所有牙齿都出现氟斑牙。在第3组中,早期和晚期形成的牙齿氟斑牙很少,而在开始服用氟化物片剂后的几年内形成的牙齿则受到氟斑牙的影响。