Cai Diming, Parajuly Shyam Sundar, Wang Huiyao, Wang Xiaoling, Ling Wenwu, Song Bin, Li Yongzhong, Luo Yan
Department of Ultrasound, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China.
Training Department of Resident Doctor, West China School of Medicine, Sichuan University, Chengdu, Sichuan 610041, P.R. China.
Exp Ther Med. 2016 Nov;12(5):3189-3194. doi: 10.3892/etm.2016.3760. Epub 2016 Sep 30.
Contrast-enhanced ultrasound (CEUS) has been used for diagnosing acute pancreatitis (AP), particularly severe acute pancreatitis (SAP). However, the diagnostic difference between CEUS and conventional ultrasonography (CUS) for AP and SAP has not been reported. The aim of the present study was to investigate the diagnostic accuracy of CUS and CEUS for AP. A total of 196 patients clinically diagnosed with AP were selected. All patients underwent CUS, CEUS and contrast-enhanced computed tomography (CECT) within 72 h. CECT was considered the gold standard. Pancreatic size, peripancreatic fluid collection (PPFC) and splenic vessel complications were the variables observed by CUS and CEUS. The differences in the variables among the three methods were analyzed using the χ test and statistical analysis software. Significant differences in pancreatic size, PPFC and splenic vessel complications in AP were observed between CEUS and CUS (P<0.05). χ test results indicated that CEUS significantly differed from CUS in terms of having a higher diagnostic accuracy for AP and SAP (P<0.05). The results indicate that CEUS is a reliable method for the diagnosis and monitoring of AP and SAP, and may be substituted for CECT.
超声造影（CEUS）已被用于诊断急性胰腺炎（AP），尤其是重症急性胰腺炎（SAP）。然而，尚未有关于CEUS与传统超声检查（CUS）对AP和SAP诊断差异的报道。本研究的目的是探讨CUS和CEUS对AP的诊断准确性。共选取了196例临床诊断为AP的患者。所有患者在72小时内接受了CUS、CEUS和对比增强计算机断层扫描（CECT）检查。CECT被视为金标准。胰腺大小、胰腺周围液体积聚（PPFC）和脾血管并发症是CUS和CEUS观察的变量。使用χ检验和统计分析软件分析三种方法之间变量的差异。CEUS和CUS在AP患者的胰腺大小、PPFC和脾血管并发症方面存在显著差异（P<0.05）。χ检验结果表明，CEUS在对AP和SAP的诊断准确性方面与CUS有显著差异（P<0.05）。结果表明，CEUS是诊断和监测AP和SAP的可靠方法，并且可能替代CECT。
